Recent advances in genome engineering provide newfound control over a plant's genetic
material. It is now possible for most bench scientists to alter DNA in living plant cells in a …

Smc5 and Smc6, together with the kleisin Nse4, form the heart of the enigmatic and poorly
understood Smc5/6 complex, which is frequently viewed as a cousin of cohesin and …

Cryptochromes (CRYs) act as blue-light photoreceptors that regulate development and
circadian rhythms in plants and animals and as navigating magnetoreceptors in migratory …

DNA damage threatens the integrity of the genome and has potentially lethal consequences
for the organism. Plant DNA is under continuous assault from endogenous and …

Improved methods for engineering sequence-specific nucleases, including zinc finger
nucleases (ZFNs) and TAL effector nucleases (TALENs), have made it possible to precisely …

Genome duplication, which results in polyploidy, is disruptive to fundamental biological
processes. Genome duplications occur spontaneously in a range of taxa and problems such …

DNA damage is normally detrimental to living organisms. Here we show that it can also
serve as a signal to promote immune responses in plants. We found that the plant immune …

The cohesin complex, named for its key role in sister chromatid cohesion, also plays critical
roles in gene regulation and DNA repair. It performs all three functions in single cell …

The structural maintenance of chromosomes (Smc) proteins regulate nearly all aspects of
chromosome biology and are critical for genomic stability. In eukaryotes, six Smc proteins …

Key message This review summarises the recent progress in DSB-induced gene targeting
by homologous recombination in plants. We are getting closer to efficiently inserting genes …