Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

[HTML][HTML] Cyclodextrins and derivatives in drug delivery: New developments, relevant clinical trials, and advanced products

G Kali, S Haddadzadegan, A Bernkop-Schnürch - Carbohydrate Polymers, 2024 - Elsevier
Cyclodextrins (CD) and derivatives are functional excipients that can improve the
bioavailability of numerous drugs. Because of their drug solubility improving properties they …

Cyclodextrins as chiral selectors in capillary electrophoresis: Recent trends in mechanistic studies

B Chankvetadze, GKE Scriba - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
In the present review the potential of capillary electrophoresis for a better understanding of
the fine structural mechanisms of noncovalent interactions and enantioselective …

Native and substituted cyclodextrins as chiral selectors for capillary electrophoresis enantioseparations: Structures, features, application, and molecular modeling

P Peluso, B Chankvetadze - Electrophoresis, 2021 - Wiley Online Library
CDs are cyclic oligosaccharides consisting of α‐d‐glucopyranosyl units linked through 1, 4‐
linkages, which are obtained from enzymatic degradation of starch. The coexistence of …

New trends in the quality control of enantiomeric drugs: quality by design-compliant development of chiral capillary electrophoresis methods

S Orlandini, G Hancu, ZI Szabó, A Modroiu, LA Papp… - Molecules, 2022 - mdpi.com
Capillary electrophoresis (CE) is a potent method for analyzing chiral substances and is
commonly used in the enantioseparation and chiral purity control of pharmaceuticals from …

Advances of capillary electrophoresis enantioseparations in pharmaceutical analysis (2017–2020)

S Krait, ML Konjaria, GKE Scriba - Electrophoresis, 2021 - Wiley Online Library
Capillary electrophoresis is a powerful technique for the analysis of polar chiral compounds
and has been widely accepted for analytical enantioseparations of drug compounds in …

Competitive self-assembly interaction between ferrocenyl units and amino acids for entry into the cavity of β-cyclodextrin for chiral electroanalysis

D Wu, L Tan, C Ma, F Pan, W Cai, J Li… - Analytical …, 2022 - ACS Publications
At present, chiral electroanalysis of nonelectroactive chiral compounds still remains a
challenge because they cannot provide an electrochemical signal by themselves. Here, a …

[HTML][HTML] Isothermal titration calorimetry and molecular modeling study of the complex formation of daclatasvir by γ-cyclodextrin and trimethyl-β-cyclodextrin

P Peluso, D Landy, L Nakhle, R Dallocchio… - Carbohydrate …, 2023 - Elsevier
The complex formation between daclatasvir and γ-CD or heptakis (2, 3, 6-tri-O-methyl)-β-CD
(TM-β-CD) was studied by isothermal titration calorimetry and molecular modeling. Both …

Functional materials in chiral capillary electrophoresis

Q Zhang, S Xue, A Li, S Ren - Coordination Chemistry Reviews, 2021 - Elsevier
Researchers in the field of chiral science have been endeavoring to develop high-
performance analytical methods for enantioseparations. The inherent flexibility of capillary …

Comparing the extraction performance of cyclodextrin-containing supramolecular deep eutectic solvents versus conventional deep eutectic solvents by headspace …

MQ Farooq, VR Zeger, JL Anderson - Journal of Chromatography A, 2021 - Elsevier
A headspace single drop microextraction (HS-SDME) method coupled with high
performance liquid chromatography was developed to compare the extraction of eighteen …