Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Introduction Poor or inconsistent adherence to daily oral pre-exposure prophylaxis (PrEP)
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …

Each day,~ 1.7 kg of NaCl and 180 liters of water are reabsorbed by nephron segments in
humans, with urinary excretion fine tuned to meet homeostatic requirements. These tasks …

More than 40 years into the pandemic, HIV remains a global burden and as of now, there is
no cure in sight. Fortunately, highly active antiretroviral therapy (HAART) has been …

Worldwide, women face compounding reproductive health risks, including human
immunodeficiency virus (HIV), sexually-transmitted infections (STIs), and unintended …

There are many factors that contribute to hyperuricemia, including obesity, insulin
resistance, alcohol consumption, diuretic use, hypertension, renal insufficiency, genetic …

Treatment of chronic hepatitis B virus (HBV) requires lifelong daily therapy. However,
suboptimal adherence to the existing daily therapy has led to the need for ultralong-acting …

Ca2+ transport along the nephron occurs via specific transcellular and paracellular
pathways and is coupled to the transport of other electrolytes. Notably, Na+ transport …

Sodium and its associated anions are the major determinant of extracellular fluid volume,
and the reabsorption of Na+ by the kidney plays a crucial role in long-term blood pressure …

Women worldwide confront two major reproductive health challenges: the need for
contraception and protection from sexually transmitted infections, including Human …