Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Preeclampsia and gestational hypertension are common pregnancy complications
associated with adverse maternal and child outcomes. Current tools for prediction …

Defective placentation is the underlying cause of various pregnancy complications, such as
severe intrauterine growth restriction and preeclampsia. However, studies on human …

Abnormal placentation has been noticed in a variety of pregnancy complications such as
miscarriage, early-onset preeclampsia, and fetal growth restriction. Defects in the …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

The embryonic program 'epithelial-mesenchymal transition'(EMT) is activated during tumor
invasion in disseminating cancer cells. Characteristic to these cells is a loss of E-cadherin …

Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

ABSTRACT A successful pregnancy depends on the intricate and timely interactions of
maternal and fetal cells. Placental extravillous cytotrophoblast invasion involves a cellular …