Purpose Treatment of rectal cancer has changed dramatically over the last decade. The
worldwide introduction of total mesorectal excision in combination with the increasing use of …

Background For a select group of patients proctectomy with intersphincteric resection (ISR)
for low rectal cancer may be a viable alternative to abdominoperineal resection, with good …

Background Laparoscopic surgery as an alternative to open surgery in patients with rectal
cancer has not yet been shown to be oncologically safe. The aim in the COlorectal cancer …

Background Neoadjuvant chemoradiotherapy does not alter anal sphincter preservation or
postoperative complications compared with short-course radiotherapy alone in patients with …

Background Intraoperative tumour perforation, positive tumour margins, wound
complications and local recurrence are frequent difficulties with conventional …

Background Abdominoperineal excision (APE) for low rectal cancer is associated with
higher rates of circumferential resection margin (CRM) involvement and intraoperative …

Purpose Despite the major improvements that have been made due to total mesorectal
excision (TME), low rectal cancer still remains a challenge. Methods By investigating a …

Purpose: This study was designed to clarify indication and benefit of pelvic sidewall
dissection for rectal cancer. Methods: The retrospective, multicenter study collected the data …

Purpose Abdominoperineal excision (APE) of the rectum and anus for rectal cancer
continues to have greater local recurrence and poorer survival than that seen following …

Background Early observational data suggest that this approach is safe and feasible, but it is
technically challenging and the learning curve has not yet been determined. The objective of …