Dengue

MG Guzman, E Harris - The Lancet, 2015 - thelancet.com
Dengue viruses have spread rapidly within countries and across regions in the past few
decades, resulting in an increased frequency of epidemics and severe dengue disease …

[HTML][HTML] Adaptive immune responses to primary and secondary dengue virus infections

AL St. John, APS Rathore - Nature Reviews Immunology, 2019 - nature.com
Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

[HTML][HTML] Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

JYJ Tan, DE Anderson, APS Rathore… - The Journal of …, 2023 - Am Soc Clin Investig
Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients who
are severely ill, and the pathophysiology of disease is thought to be immune mediated. Mast …

[HTML][HTML] Dengue: update on clinically relevant therapeutic strategies and vaccines

M Palanichamy Kala, AL St. John… - Current Treatment Options …, 2023 - Springer
Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …

[HTML][HTML] Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-Siglec-8 antibody

S Gebremeskel, J Schanin, KM Coyle… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection represents a
global health crisis. Immune cell activation via pattern recognition receptors has been …

[HTML][HTML] Dengue infection

MG Guzman, DJ Gubler, A Izquierdo… - Nature reviews Disease …, 2016 - nature.com
Dengue is widespread throughout the tropics and local spatial variation in dengue virus
transmission is strongly influenced by rainfall, temperature, urbanization and distribution of …

Immune-mediated cytokine storm and its role in severe dengue

A Srikiatkhachorn, A Mathew, AL Rothman - Seminars in …, 2017 - Springer
Dengue remains one of the most important mosquito-borne diseases worldwide. Infection
with one of the serologically related dengue viruses (DENVs) can lead to a wide range of …

[HTML][HTML] Mast cell responses to viruses and pathogen products

JS Marshall, L Portales-Cervantes, E Leong - International Journal of …, 2019 - mdpi.com
Mast cells are well accepted as important sentinel cells for host defence against selected
pathogens. Their location at mucosal surfaces and ability to mobilize multiple aspects of …

The good, the bad, and the shocking: the multiple roles of dengue virus nonstructural protein 1 in protection and pathogenesis

DR Glasner, H Puerta-Guardo, PR Beatty… - Annual review of …, 2018 - annualreviews.org
Dengue virus (DENV) is the most prevalent medically important mosquito-borne virus in the
world. Upon DENV infection of a host cell, DENV nonstructural protein 1 (NS1) can be found …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …