Many neurodegenerative diseases such as Alzheimer's disease (AD), multiple sclerosis,
and traumatic brain injury (TBI) are associated with systemic inflammation. Inflammation …

Microdialysis is commonly used in neuroscience to obtain information about the
concentration of substances, including neurotransmitters such as dopamine (DA), in the …

Although concussion is now recognized as a major health issue, its non-lethal nature has
limited characterization of the underlying pathophysiology. In particular, potential …

Objective Neuronal loss, a key substrate of irreversible disability in multiple sclerosis (MS), is
a recognized feature of MS cortical pathology of which the cause remains unknown. Fibrin …

Background: String vessels are collapsed basement membrane without endothelium and
have no function in circulation. String vessel formation contributes to vascular degeneration …

Microdialysis sampling in the brain is employed frequently in the chemical analysis of
neurological function and disease, but implanting the probes, which are substantially larger …

Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example,
increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer's …

Over several decades, biomaterial scientists have developed materials to spur axonal
regeneration and limit secondary injury and tested these materials within preclinical animal …

To modulate the surface properties of collagen and subsequent cell–surface interactions, a
method was developed to transfer protein patterns from glass coverslips to collagen type I …

Besides causing neuronal damage, traumatic brain injury (TBI) is involved in memory
reduction, which can be a result of alterations in vasculo-neuronal interactions. Inflammation …