The travel diaries of tetanus and botulinum neurotoxins

S Surana, AP Tosolini, IFG Meyer, AD Fellows… - Toxicon, 2018 - Elsevier
Abstract Tetanus (TeNT) and botulinum (BoNT) neurotoxins, the causative agents of tetanus
and botulism, respectively, are the most potent toxic molecules known to mankind. This …

Botulinum toxin as a pain killer: players and actions in antinociception

DW Kim, SK Lee, J Ahnn - Toxins, 2015 - mdpi.com
Botulinum neurotoxins (BoNTs) have been widely used to treat a variety of clinical ailments
associated with pain. The inhibitory action of BoNTs on synaptic vesicle fusion blocks the …

The long journey of botulinum neurotoxins into the synapse

A Rummel - Toxicon, 2015 - Elsevier
Botulinum neurotoxins (BoNT) cause the disease botulism, a flaccid paralysis of the muscle.
They are also very effective, widely used medicines applied locally in sub-nanogram …

Structural basis of the pH-dependent assembly of a botulinum neurotoxin complex

T Matsui, S Gu, K Lam, LG Carter, A Rummel… - Journal of molecular …, 2014 - Elsevier
Botulinum neurotoxins (BoNTs) are among the most poisonous biological substances
known. They assemble with non-toxic non-hemagglutinin (NTNHA) protein to form the …

Uptake of clostridial neurotoxins into cells and dissemination

C Connan, MR Popoff - Uptake and Trafficking of Protein Toxins, 2017 - Springer
Clostridial neurotoxins, botulinum neurotoxins (BoNT) and tetanus neurotoxin (TeNT), are
potent toxins, which are responsible for severe neurological diseases in man and animals …

The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein

K Lam, R Qi, S Liu, A Kroh, G Yao, K Perry, A Rummel… - Toxicon, 2018 - Elsevier
Botulinum neurotoxins (BoNTs) are causative agents of the life-threatening disease
botulism. They are naturally produced by species of the bacteria Clostridium botulinum as …

Translocation of botulinum neurotoxin serotype A and associated proteins across the intestinal epithelia

TI Lam, LH Stanker, K Lee, R Jin… - Cellular …, 2015 - Wiley Online Library
Botulinum neurotoxins (BoNTs) are some of the most poisonous natural toxins. Botulinum
neurotoxins associate with neurotoxin‐associated proteins (NAPs) forming large complexes …

[HTML][HTML] Sensory Symptoms Associated with Aesthetic Botulinum Toxin A Treatments

N Corduff - Plastic and Reconstructive Surgery–Global Open, 2022 - journals.lww.com
Background: A retrospective review of patients who switched from onabotulinumtoxinA
(onaA) and/or abobotulinumtoxinA (aboA) to incobotulinumtoxinA (incoA) found anecdotal …

High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex

K Lee, KH Lam, AM Kruel, K Perry, A Rummel… - … and biophysical research …, 2014 - Elsevier
Botulinum neurotoxins (BoNTs) are produced as progenitor toxin complexes (PTCs) by
Clostridium botulinum. The PTCs are composed of BoNT and non-toxic neurotoxin …

Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics

K Lee, KH Lam, AM Kruel, S Mahrhold, K Perry… - Toxicon, 2015 - Elsevier
Botulinum neurotoxins (BoNTs) cause the disease botulism manifested by flaccid paralysis
that could be fatal to humans and animals. Oral ingestion of the toxin with contaminated food …