To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

Zinc-finger proteins (ZNFs) are one of the most abundant groups of proteins and have a
wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are …

Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar"
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …

Background Glioma-associated microglia/macrophages (GAMs) comprise macrophages of
peripheral origin and brain-intrinsic microglia, which support tumor progression. Chemokine …

The tumor microenvironment (TME) is a complex interconnected network of immune cells,
fibroblasts, blood vessels, and extracellular matrix surrounding the tumor. Because of its …

Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a
peak incidence in adolescents and young adults, conventional and dedifferentiated …

Currently, acquired resistance to cisplatin (DDP) is a substantial obstacle to reducing the
morbidity and mortality due to ovarian malignant tumors. Nevertheless, cisplatin plays a vital …

Articular adipose tissue is a ubiquitous component of human joints, and adiponectin is a
protein hormone secreted predominantly by differentiated adipocytes and involved in energy …

As a kind of malignant tumors, hepatocellular carcinoma (HCC) has been studied
continuously, but the mechanisms are not well understood. Circular RNAs (circRNAs) are …

Clinical outcome prediction is major concern to patients with cancer. Various molecular
markers in various carcinomas have been identified in the past few decades. However …