Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

KJ Ressler, S Berretta, VY Bolshakov… - Nature Reviews …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

Psychological health, well-being, and the mind-heart-body connection: a scientific statement from the American Heart Association

GN Levine, BE Cohen, Y Commodore-Mensah… - Circulation, 2021 - Am Heart Assoc
As clinicians delivering health care, we are very good at treating disease but often not as
good at treating the person. The focus of our attention has been on the specific physical …

The effects of chronic stress on the human brain: From neurotoxicity, to vulnerability, to opportunity

SJ Lupien, RP Juster, C Raymond, MF Marin - Frontiers in …, 2018 - Elsevier
For the last five decades, science has managed to delineate the mechanisms by which
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …

The role of the hippocampus in flexible cognition and social behavior

RD Rubin, PD Watson, MC Duff… - Frontiers in human …, 2014 - frontiersin.org
Successful behavior requires actively acquiring and representing information about the
environment and people, and manipulating and using those acquired representations …

Post-traumatic stress disorder and cardiovascular disease

D Edmondson, R von Känel - The Lancet Psychiatry, 2017 - thelancet.com
In this paper, a first in a Series of two, we look at the evidence for an association of post-
traumatic stress disorder with incident cardiovascular disease risk and the mechanisms that …

Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia

A Etkin, TD Wager - American journal of Psychiatry, 2007 - Am Psychiatric Assoc
Objective: The study of human anxiety disorders has benefited greatly from functional
neuroimaging approaches. Individual studies, however, vary greatly in their findings. The …

Chronic stress, cognitive functioning and mental health

MF Marin, C Lord, J Andrews, RP Juster, S Sindi… - Neurobiology of learning …, 2011 - Elsevier
This review aims to discuss the evidence supporting the link between chronic stress,
cognitive function and mental health. Over the years, the associations between these …

The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology

EI Martin, KJ Ressler, E Binder… - Psychiatric …, 2009 - psych.theclinics.com
This work was supported by National Institute of Health (NIH) grants MH-541380, MH-
77083, MH-69056, MH-58922, MH-42088, MH071537, and DA-019624; the Doris Duke …

Relations among posttraumatic stress disorder, comorbid major depression, and HPA function: a systematic review and meta-analysis

MC Morris, BE Compas, J Garber - Clinical psychology review, 2012 - Elsevier
Exposure to traumatic stress is associated with increased risk for posttraumatic stress
disorder (PTSD) and alterations of hypothalamic–pituitary–adrenocortical (HPA) function …

Neighborhood matters: divergent patterns of stress-induced plasticity across the brain

S Chattarji, A Tomar, A Suvrathan, S Ghosh… - Nature …, 2015 - nature.com
The fact that exposure to severe stress leads to the development of psychiatric disorders
serves as the basic rationale for animal models of stress disorders. Clinical and …