The use of low dose methotrexate in rheumatoid arthritis—are we entering a new era of therapeutic drug monitoring and pharmacogenomics?

L Stamp, R Roberts, M Kennedy, M Barclay… - Biomedicine & …, 2006 - Elsevier
Methotrexate (MTX) is one of the most commonly used medications in the treatment of
rheumatoid arthritis (RA). It has proven efficacy as a sole agent as well as in combination …

Counseling for medical abortion

V Breitbart - American journal of obstetrics and gynecology, 2000 - Elsevier
Counseling and education are correlated with women's satisfaction with all abortion care.
They often assume a larger role in medical abortion because the patient is a more active …

Effects of methotrexate on trophoblast proliferation and local immune responses.

JA DeLoia, AM Stewart-Akers… - Human reproduction …, 1998 - academic.oup.com
Methotrexate is a folic acid analogue that has been used successfully for the treatment of
ectopic pregnancy and, in conjunction with misoprostol, for medical abortions of early …

Early medical termination pregnancy with methotrexate and misoprostol in lower segment cesarean section cases

R Gautam, V Agrawal - Journal of obstetrics and gynaecology …, 2003 - Wiley Online Library
Aim: The aim of the study was to investigate the efficacy of methotrexate and misoprostol for
the medical termination of early pregnancy with previous cesarean section. Methods: Sixty …

Fetal methotrexate and misoprostol exposure: the past revisited

M Wheeler, P O'Meara, M Stanford - Teratology, 2002 - Wiley Online Library
Background Fetal aminopterin/methotrexate syndrome was described nearly 50 years ago
when these agents were first used as abortifacients. Physicians essentially stopped using …

Success rates and estimation of gestational age for medical abortion vary with transvaginal ultrasonographic criteria

MD Creinin, H Jerald - American journal of obstetrics and gynecology, 1999 - Elsevier
Objective: Our purpose was to evaluate differences in gestational age and success rates for
medical abortion patients obtained by using several nomograms for mean sac diameter and …

Sex hormones, hemostasis and early pregnancy loss

DB Nelson, RB Ness, JA Grisso… - Archives of gynecology and …, 2002 - Springer
Aims: This study was designed to determine the association between coagulation factors
and spontaneous abortion adjusting for sex steroids and to examine the influence of sex …

Trophoblastic neoplasms

K Benirschke, GJ Burton, RN Baergen… - Pathology of the human …, 2012 - Springer
Among trophoblastic neoplasms, choriocarcinoma is the most well-known. The classification
of gestational trophoblastic disease (GTD) has been alluded to in the previous chapter, and …

Methotrexate induces apoptosis of postpartum placental cytotrophoblasts

H Yan, Z Li, Z Yan, X Li, X Li, L Yu, C Su… - Cells Tissues Organs, 2017 - karger.com
Background: Though methotrexate (MTX) is known to inhibit proliferation of trophoblasts
derived from ectopic and intrauterine pregnancies, its action on trophoblasts derived from …

Methotrexate treatment of ectopic pregnancy: Observations on the medical literature

TP Collins - The Linacre Quarterly, 2003 - journals.sagepub.com
This essay grew out of a presentation made to the medical staff of the hospital where I
practice. I am a pathologist and claim no special expertise in the matter, however the topic of …