International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

DM Wingerchuk, B Banwell, JL Bennett, P Cabre… - Neurology, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies …

MRI characteristics of neuromyelitis optica spectrum disorder: an international update

HJ Kim, F Paul, MA Lana-Peixoto, S Tenembaum… - Neurology, 2015 - AAN Enterprises
Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to
involve only the optic nerves and spinal cord. However, the discovery of highly specific anti …

Clinical spectrum and prognostic value of CNS MOG autoimmunity in adults: the MOGADOR study

A Cobo-Calvo, A Ruiz, E Maillart, B Audoin, H Zephir… - Neurology, 2018 - AAN Enterprises
Objective To describe clinical and radiologic features associated with myelin
oligodendrocyte glycoprotein antibodies (MOG-Ab) in a large French nationwide adult …

Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS)

C Trebst, S Jarius, A Berthele, F Paul, S Schippling… - Journal of …, 2014 - Springer
Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

Aquaporin 4 and neuromyelitis optica

MC Papadopoulos, AS Verkman - The Lancet Neurology, 2012 - thelancet.com
Neuromyelitis optica is an inflammatory demyelinating disorder of the CNS. The discovery of
circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) …

Pathology of multiple sclerosis: where do we stand?

BFG Popescu, I Pirko… - … : Lifelong Learning in …, 2013 - journals.lww.com
MS is heterogeneous with respect to clinical, genetic, radiographic, and pathologic features;
surrogate MRI, clinical, genetic, serologic, and/or CSF markers for each of the four …

The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica

CF Lucchinetti, Y Guo, BFG Popescu… - Brain …, 2014 - Wiley Online Library
Neuromyelitis optica (NMO) is a disabling autoimmune astrocytopathy characterized by
typically severe and recurrent attacks of optic neuritis and longitudinally extensive myelitis …

Pathology of demyelinating diseases

BFG Popescu, CF Lucchinetti - Annual Review of Pathology …, 2012 - annualreviews.org
There has been significant progress in our understanding of the pathology and
pathogenesis of central nervous system inflammatory demyelinating diseases …

Area postrema syndrome: Frequency, criteria, and severity in AQP4-IgG–positive NMOSD

E Shosha, D Dubey, J Palace, I Nakashima, A Jacob… - Neurology, 2018 - AAN Enterprises
Objective To define the frequency, duration, and severity of intractable nausea, vomiting, or
hiccups in aquaporin-4–immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica …

The history of neuromyelitis optica

S Jarius, B Wildemann - Journal of neuroinflammation, 2013 - Springer
The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of
patients in 2004 has revived interest in neuromyelitis optica (NMO). While the history of …