Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Activity‐based smart AIEgens for detection, bioimaging, and therapeutics: Recent progress and outlook

H Li, H Kim, J Han, VN Nguyen, X Peng, J Yoon - Aggregate, 2021 - Wiley Online Library
Activity‐based approaches for designing AIEgens possess prominent advantages including
high selectivity, sensitivity, and signal‐to‐noise ratio, and they have received more attention …

Fluorescent probes for biomolecule detection under environmental stress

X Han, Y Wang, Y Huang, X Wang, J Choo… - Journal of Hazardous …, 2022 - Elsevier
The use of fluorescent probes in visible detection has been developed over the last several
decades. Biomolecules are essential in the biological processes of organisms, and their …

In vitro anticancer activity and in vivo biodistribution of rhenium (I) tricarbonyl aqua complexes

KM Knopf, BL Murphy, SN MacMillan… - Journal of the …, 2017 - ACS Publications
Seven rhenium (I) complexes of the general formula fac-[Re (CO) 3 (NN)(OH2)]+ where NN=
2, 2′-bipyridine (8), 4, 4′-dimethyl-2, 2′-bipyridine (9), 4, 4′-dimethoxy-2, 2′-bipyridine …

Rational design of fluorescein-based fluorescence probes. Mechanism-based design of a maximum fluorescence probe for singlet oxygen

K Tanaka, T Miura, N Umezawa, Y Urano… - Journal of the …, 2001 - ACS Publications
Fluorescein is one of the best available fluorophores for biological applications, but the
factors that control its fluorescence properties are not fully established. Thus, we initiated a …

[HTML][HTML] Guidelines for the selection of functional assays to evaluate the hallmarks of cancer

O Menyhárt, H Harami-Papp, S Sukumar… - … et Biophysica Acta (BBA …, 2016 - Elsevier
The hallmarks of cancer capture the most essential phenotypic characteristics of malignant
transformation and progression. Although numerous factors involved in this multi-step …

Development of a zinc ion-selective luminescent lanthanide chemosensor for biological applications

K Hanaoka, K Kikuchi, H Kojima, Y Urano… - Journal of the …, 2004 - ACS Publications
Detection of chelatable zinc (Zn2+) in biological studies has attracted much attention
recently, because chelatable Zn2+ plays important roles in many biological systems …

Design, synthesis and biological application of chemical probes for bio-imaging

K Kikuchi - Chemical Society Reviews, 2010 - pubs.rsc.org
Biological imaging has revealed many new biological findings, among them GFP and other
fluorescent proteins and small molecule based fluorescent probes have been widely used …

Specific cell surface protein imaging by extended self-assembling fluorescent turn-on nanoprobes

K Mizusawa, Y Takaoka, I Hamachi - Journal of the American …, 2012 - ACS Publications
Visualization of tumor-specific protein biomarkers on cell membranes has the potential to
contribute greatly to basic biological research and therapeutic applications. We recently …

Design and synthesis of an enzyme-cleavable sensor molecule for phosphodiesterase activity based on fluorescence resonance energy transfer

H Takakusa, K Kikuchi, Y Urano… - Journal of the …, 2002 - ACS Publications
Ratiometric measurement is a technique that can provide precise data and even quantitative
detection. To carry out ratiometric measurements, it is necessary that the sensor molecule …