[HTML][HTML] Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids

AQ Khan, K Rashid, AA AlAmodi, MV Agha… - Biomedicine & …, 2021 - Elsevier
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of
human diseases including cancer. In this line, now it has become evident that ROS …

Functional studies of plant latex as a rich source of bioactive compounds: focus on proteins and alkaloids

J Gracz-Bernaciak, O Mazur, R Nawrot - International journal of molecular …, 2021 - mdpi.com
Latex, a sticky emulsion produced by specialized cells called laticifers, is a crucial part of a
plant's defense system against herbivory and pathogens. It consists of a broad spectrum of …

Quercetin induces cytochrome‐c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and …

K Bishayee, S Ghosh, A Mukherjee… - Cell …, 2013 - Wiley Online Library
Objectives Small aromatic compounds like flavonoids can intercalate with DNA molecules
bringing about conformational changes leading to reduced replication and transcription …

Crosstalk between Phosphoinositide 3‐kinase/Akt signaling pathway with DNA damage response and oxidative stress in cancer

A Karimian, SM Mir, H Parsian… - Journal of cellular …, 2019 - Wiley Online Library
Abstract The phosphatidylinositol 3‐kinases (PI3K)/Akt signaling pathway is one of the well‐
characterized and most important signaling pathways activated in response to DNA …

Arctiin inhibits cervical cancer cell migration and invasion through suppression of S100A4 expression via PI3K/Akt pathway

CY Lee, MC Hsin, PN Chen, CW Lin, PH Wang… - Pharmaceutics, 2022 - mdpi.com
Arctiin, a lignan glycoside, is isolated from Arctium lappa L. The anticancer effects of arctiin
have been demonstrated in several studies. However, no research has been conducted on …

Alkaloids in Chelidonium majus L: a review of its phytochemistry, pharmacology and toxicology

XL Li, YP Sun, M Wang, ZB Wang… - Frontiers in …, 2024 - frontiersin.org
Chelidonium majus L.(C. majus), commonly known as “Bai Qu Cai” in China, belongs to the
genus Chelidonium of the Papaveraceae family. It has rich medicinal value, such as …

[HTML][HTML] The potentized homeopathic drug, Lycopodium clavatum (5C and 15C) has anti-cancer effect on hela cells in vitro.

A Samadder, S Das, J Das, A Paul, N Boujedaini… - Journal of acupuncture …, 2013 - Elsevier
Cancer is a disease that needs a multi-faceted approach from different systems of medicine.
The purpose of this study was to evaluate whether homeopathically-potentized ultra-high …

[HTML][HTML] Chelidonine suppresses LPS-Induced production of inflammatory mediators through the inhibitory of the TLR4/NF-κB signaling pathway in RAW264. 7 …

W Liao, X He, Z Yi, W Xiang, Y Ding - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Chelidonine is one of the alkaloids of Chelidonium majus, which has broad pharmacological
activities, including anti-inflammatory. Despite chelidonine has been shown to exhibit anti …

The potential of Chinese herbal medicines in the treatment of cervical cancer

YH Hsiao, CW Lin, PH Wang… - Integrative Cancer …, 2019 - journals.sagepub.com
Cervical cancer is a global health issue and places a considerable economic and medical
burden on society. Thus, a concerted effort to improve the treatment of cervical cancer is …

Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

ZH Zhang, C Mi, KS Wang, Z Wang, MY Li… - Phytotherapy …, 2018 - Wiley Online Library
Nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) is a complex that
regulates several hundreds of genes, including those involved in immunity and …