Progress report: Antimicrobial drug discovery in the resistance era
Antibiotic resistance continues to be a most serious threat to public health. This situation
demands that the scientific community increase their efforts for the discovery of alternative …
demands that the scientific community increase their efforts for the discovery of alternative …
Evaluating intervention strategies in controlling coronavirus disease 2019 (COVID-19) spread in care homes: An agent-based model
S Howick, D McLafferty, GH Anderson… - Infection Control & …, 2021 - cambridge.org
Background: Care homes are vulnerable to widespread transmission of severe acute
respiratory coronavirus virus 2 (SARS-CoV-2) with poor outcomes for staff and residents …
respiratory coronavirus virus 2 (SARS-CoV-2) with poor outcomes for staff and residents …
A review of epidemiological models of Clostridioides difficile transmission and control (2009–2021)
Clostridioides difficile is the leading cause of infectious diarrhea and one of the most
common healthcare-acquired infections worldwide. We performed a systematic search and …
common healthcare-acquired infections worldwide. We performed a systematic search and …
Evaluating the impact of testing strategies for the detection of nosocomial COVID-19 in English hospitals through data-driven modeling
Introduction During the first wave of the COVID-19 pandemic 293,204 inpatients in England
tested positive for SARS-CoV-2. It is estimated that 1% of these cases were hospital …
tested positive for SARS-CoV-2. It is estimated that 1% of these cases were hospital …
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and …
Antivirulence agents targeting endospore-transmitted Clostridioides difficile infections are
urgently needed. C. difficile-specific DNA adenine methyltransferase (CamA) is required for …
urgently needed. C. difficile-specific DNA adenine methyltransferase (CamA) is required for …
Early coronavirus disease 2019 (COVID-19) pandemic effects on individual-level risk for healthcare-associated infections in hospitalized patients
TS Farthing, A Jolley, KB Nickel, C Hill… - Infection Control & …, 2023 - cambridge.org
Objective: We compared the individual-level risk of hospital-onset infections with multidrug-
resistant organisms (MDROs) in hospitalized patients prior to and during the coronavirus …
resistant organisms (MDROs) in hospitalized patients prior to and during the coronavirus …
[HTML][HTML] A framework for conceptualising hybrid system dynamics and agent-based simulation models
S Howick, I Megiddo - European Journal of Operational Research, 2024 - Elsevier
The growing complexity of systems and problems that stakeholders from the private and
public sectors have sought advice on has led systems modellers to increasingly use …
public sectors have sought advice on has led systems modellers to increasingly use …
Agent-based modeling of C. difficile spread in hospitals: assessing contribution of high-touch vs. Low-touch surfaces and inoculations' containment Impact
Health issues and pandemics remain paramount concerns in the contemporary era.
Clostridioides Difficile Infection (CDI) stands out as a critical healthcare-associated infection …
Clostridioides Difficile Infection (CDI) stands out as a critical healthcare-associated infection …
[HTML][HTML] Health care–associated Clostridioides difficile infection: Learning the perspectives of health care workers to build successful strategies
V Lev, T Anbarchian, H Yao, A Bhat, P Britt… - American Journal of …, 2024 - Elsevier
Background Clostridioides difficile (C difficile) is one of the most common health care–
associated infections that negatively impact patient care and health care costs. This study …
associated infections that negatively impact patient care and health care costs. This study …
Inactivation of Spores and Vegetative Forms of Clostridioides difficile by Chemical Biocides: Mechanisms of Biocidal Activity, Methods of Evaluation, and …
Clostridioides difficile infections (CDIs) are the most common cause of acquired diseases in
hospitalized patients. Effective surface disinfection, focused on the inactivation of the spores …
hospitalized patients. Effective surface disinfection, focused on the inactivation of the spores …