[HTML][HTML] Immunometabolic effect of cholesterol in hepatitis C infection: implications in clinical management and antiviral therapy

K González-Aldaco, LA Torres-Reyes… - Annals of …, 2018 - Elsevier
Hepatitis C virus (HCV) is a lipid-enveloped virion particle that causes infection to the liver,
and as part of its life cycle, it disrupts the host lipid metabolic machinery, particularly the …

IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients

N Echeverría, D Chiodi, P López, A Sanchez Ciceron… - Virology journal, 2018 - Springer
Background Host single-nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B)
locus are associated with sustained virological response to antiviral therapy and with …

The impact of genetic variations in sofosbuvir metabolizing enzymes and innate immunity mediators on treatment outcome in HCV-infected patients

MK Ibrahim, M AbdElrahman, NGB El Din, S Tawfik… - Microbial …, 2022 - Elsevier
Hepatitis C virus (HCV) is the leading cause of liver diseases worldwide. At present,
combinations of different classes of direct-acting antiviral agents (DAAs) are used as …

Impact of IL28B gene polymorphism on efficacy and safety of direct acting antivirals in hepatitis C Egyptian patients

AHIM Ebid, OA Ahmed, SH Agwa… - International Journal of …, 2020 - Springer
Background Hepatitis C virus infection is one of the major causes of liver cirrhosis and
hepatocellular carcinoma worldwide. IL28B gene polymorphism has a direct relation to the …

The effect of the first-generation HCV-protease inhibitors boceprevir and telaprevir and the relation to baseline NS3 resistance mutations in genotype 1: experience …

M Kjellin, T Wesslén, E Löfblad… - Upsala journal of …, 2018 - Taylor & Francis
Background: The clinical experience with protease-inhibitor (PI) triple regimen appears
disappointing regarding effect, side effects, high work load, and costs. This real-world study …

Interleukin 28A. rs12980602 and interleukin 28B. rs8103142 genotypes could be protective against HCV infection among Egyptians

ZA Zakaria, S Knapp, M Hashem, H Zaghla… - Immunologic …, 2019 - Springer
Previous studies showed that interleukin (IL)-28B gene polymorphisms were associated with
hepatitis C Virus (HCV) infection and treatment outcomes. We tested whether single …

Predictive potential of IL28B gene in HCV patients, resistant to daclatasvir and sofosbuvir in KPK population

S Sardar, S Muhammad, M Haq… - Journal of Ayub …, 2023 - demo.ayubmed.edu.pk
Background: Recently various combinations of direct acting antivirals (DAAs) have been
tried successfully. Sofosbuvir+ Daclatasvir combination has been used with promising …

[PDF][PDF] IL28B rs12979860 gene polymorphism and sofosbuvir-based therapy response in HCV-infected Pakistani patients.

M Asim, A Javed, A Saeed, B Adeel… - … Journal of Medical …, 2024 - jag.journalagent.com
Objectives: Interleukin-28B (IL-28B) gene polymorphisms play an important role in response
prediction of direct-acting antivirals (DAAs) treatment, including Sofosbuvir and Daclatasvir …

Distribution of IL28B rs12979860 and rs8099917 Genotypes in Patients with Chronic Hepatitis C Virus Infection in Tianjin, China.

K Qiao, C Trieu, Z Huo, Y Du, W Hou - Clinical Laboratory, 2018 - search.ebscohost.com
Background: Two single-nucleotide polymorphisms (SNPs) rs12979860 (C/T) and
rs8099917 (T/G), near the interleukin 28B (IL28B, also known as IFN lambda-3, IFNL3) …

[HTML][HTML] Mycro 3 also shows weak inhibitory activity against AP-1. Menu

AHIM Ebid, OA Ahmed, SH Agwa, SM Abdel‑Motaleb… - mycro3inhibitor.com
Background Hepatitis C virus infection is one of the major causes of liver cirrhosis and
hepatocellular carcinoma worldwide. IL28B gene polymorphism has a direct relation to the …