Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

S Zhu, W Chen, A Masson, YP Li - Cell Discovery, 2024 - nature.com
The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo
differentiation into osteoblasts. This differentiation process plays a crucial role in bone …

Osteoimmunology: the conceptual framework unifying the immune and skeletal systems

K Okamoto, T Nakashima, M Shinohara… - Physiological …, 2017 - journals.physiology.org
The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

863 genomes reveal the origin and domestication of chicken

MS Wang, M Thakur, MS Peng, YU Jiang, LAF Frantz… - Cell research, 2020 - nature.com
Despite the substantial role that chickens have played in human societies across the world,
both the geographic and temporal origins of their domestication remain controversial. To …

Osteoblast Differentiation and Bone Matrix Formation In Vivo and In Vitro

HC Blair, QC Larrouture, Y Li, H Lin… - … Engineering Part B …, 2017 - liebertpub.com
We review the characteristics of osteoblast differentiation and bone matrix synthesis. Bone in
air breathing vertebrates is a specialized tissue that developmentally replaces simpler solid …

Role of thyroid hormones in skeletal development and bone maintenance

JHD Bassett, GR Williams - Endocrine reviews, 2016 - academic.oup.com
The skeleton is an exquisitely sensitive and archetypal T3-target tissue that demonstrates
the critical role for thyroid hormones during development, linear growth, and adult bone …

Management of endocrine disease: secondary osteoporosis: pathophysiology and management

F Mirza, E Canalis - European journal of endocrinology, 2015 - academic.oup.com
Osteoporosis is a skeletal disorder characterized by decreased mass and compromised
bone strength predisposing to an increased risk of fractures. Although idiopathic …

Thyroid hormone diseases and osteoporosis

AP Delitala, A Scuteri, C Doria - Journal of clinical medicine, 2020 - mdpi.com
Thyroid hormones are essential for normal skeletal development and normal bone
metabolism in adults but can have detrimental effects on bone structures in states of thyroid …

Subclinical thyroid dysfunction and fracture risk: a meta-analysis

MR Blum, DC Bauer, TH Collet, HA Fink, AR Cappola… - Jama, 2015 - jamanetwork.com
Importance Associations between subclinical thyroid dysfunction and fractures are unclear
and clinical trials are lacking. Objective To assess the association of subclinical thyroid …

[HTML][HTML] Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish

HJ Zhao, JK Xu, ZH Yan, HQ Ren, Y Zhang - Environment International, 2020 - Elsevier
Coexposure of MPs and other contaminants adsorbed from the environment has raised
many attentions, but the understanding of the combined effects of MPs and plastic additives …

The clinical significance of subclinical thyroid dysfunction

B Biondi, DS Cooper - Endocrine reviews, 2008 - academic.oup.com
Subclinical thyroid disease (SCTD) is defined as serum free T4 and free T3 levels within
their respective reference ranges in the presence of abnormal serum TSH levels. SCTD is …