Polygenic risk scores (PRSs) summarize the genetic predisposition of a complex human trait
or disease and may become a valuable tool for advancing precision medicine. However …

Research demonstrates the important role of genetic factors in attention-deficit/hyperactivity
disorder (ADHD). DNA sequencing of families provides a powerful approach for identifying …

Nearly two hundred common-variant depression risk loci have been identified by genome-
wide association studies (GWAS). However, the impact of rare coding variants on …

Previous genetic studies of venous thromboembolism (VTE) have been largely limited to
common variants, leaving the genetic determinants relatively incomplete. We performed an …

Alcohol consumption is a heritable behavior seriously endangers human health. However,
genetic studies on alcohol consumption primarily focuses on common variants, while …

Although rare neurodevelopmental conditions have a large Mendelian component, common
genetic variants also contribute to risk,. However, little is known about how this polygenic …

Socioeconomic status (SES) impacts health and life-course outcomes. This genome-wide
association study (GWAS) of sociologically informed occupational status measures (ISEI …

Twin and genomic studies indicate that genes play an important role in the development of
cognitive ability. However, data limitations have made it difficult to pinpoint specific genes …

There is limited evidence on the effects of intrauterine chromium (Cr) exposure on children's
cognitive developmental delay (CDD). Further, little is known about the genetic factors in …

Socioeconomic status (SES) is a critical factor in determining health outcomes and is
influenced by genetic and environmental factors. However, our understanding of the genetic …