Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …

Wnt/β‐catenin pathway is one of the main/frequent dysregulated pathways in several tumor
types, including colon cancer. Aberrant activation of this pathway is associated with cell …

WNT/β-catenin signaling controls gene expression across biological contexts from
development and stem cell homeostasis to diseases including cancer. How β-catenin is …

Curcumin exhibits anti-tumor effects in several cancers, including colorectal carcinoma
(CRC), but the detailed mechanisms are still unclear. Here we studied the mechanisms …

ABSTRACT A new model-free method has been developed and termed the landscape
dynamic network biomarker (l-DNB) methodology. The method is based on bifurcation …

Amine oxidase copper-containing 1 (AOC1) is considered an oncogene in many types of
tumors. Nevertheless, there have been no investigations of AOC1 and its regulatory …

Purpose: Gene fusions involving R-spondin (RSPOfp) and RNF43 mutations have been
shown to drive Wnt-dependent tumor initiation in colorectal cancer. Herein, we aimed to …

Cervical cancer is among the most commonly diagnosed cancer in women, supporting the
need for identification of novel prognostic and predictive biomarkers to predict the risk of …

Results Our results showed that combination of quercetin and 5-FU exhibited greater
cytotoxic efficacy than did 5-FU alone. Co-administration of both drugs either in combination …

Background Sex-determining region Y-box containing gene 30 (SOX30) is a newly identified
tumor-associated gene in several types of cancer. However, whether SOX30 is involved in …