Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

C Heinzle, Z Erdem, J Paur… - Current …, 2014 - ingentaconnect.com
Fibroblast growth factors (FGF) and their tyrosine kinase receptors (FGFR) support cell
proliferation, survival and migration during embryonic development, organogenesis and …

FGFR4 transmembrane domain polymorphism and cancer risk: a meta-analysis including 8555 subjects

W Xu, Y Li, X Wang, B Chen, Y Wang, S Liu, J Xu… - European journal of …, 2010 - Elsevier
Fibroblast growth factor receptor 4 (FGFR4), belonging to the receptor tyrosine kinase family,
is involved in cancer initiation and progression. The FGFR4 Gly388Arg polymorphism in the …

Effects of FGFR4 G388R, V10I polymorphisms on the likelihood of cancer

T Peng, Y Sun, Z Lv, Z Zhang, Q Su, H Wu, W Zhang… - Scientific reports, 2021 - nature.com
The correlation between G388R or V10I polymorphisms of fibroblast growth factor receptor
(FGFR) 4 gene and the risk of carcinoma has been investigated previously, but the results …

[HTML][HTML] Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men

R Cartwright, A Mangera, KAO Tikkinen, P Rajan… - European urology, 2014 - Elsevier
Context Although family studies have shown that male lower urinary tract symptoms (LUTS)
are highly heritable, no systematic review exists of genetic polymorphisms tested for …

Gene variants in the angiogenesis pathway and prostate cancer

EK Amankwah, TA Sellers, JY Park - Carcinogenesis, 2012 - academic.oup.com
Although the causes of prostate cancer are still unknown, numerous studies support the role
of genetic factors in the development and progression of this disease. Single nucleotide …

FGFR4 Gly388Arg polymorphism contributes to prostate cancer development and progression: A meta-analysis of 2618 cases and 2305 controls

B Xu, N Tong, SQ Chen, LX Hua, ZJ Wang, ZD Zhang… - BMC cancer, 2011 - Springer
Background Fibroblast growth factor receptor 4 (FGFR4) displays multiple biological
activities, including mitogenic and angiogenic activity, and plays important roles in the …

The fibroblast growth factor receptor-4 Arg388 allele is associated with gastric cancer progression

Y Ye, Y Shi, Y Zhou, C Du, C Wang, H Zhan… - Annals of surgical …, 2010 - Springer
Background Fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism, located
in the FGFR4 gene exon 9, was reported to be associated with malignant tumors prognosis; …

[HTML][HTML] Functional FGFR4 Gly388Arg polymorphism contributes to cancer susceptibility: Evidence from meta-analysis

SW Xiong, J Ma, F Feng, W Fu, SR Shu, T Ma, C Wu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Fibroblast growth factor receptor 4 (FGFR4) is a member of receptor tyrosine kinase family. A
functional Gly388Arg (rs351855 G> A) polymorphism in FGFR4 gene causes a glycine-to …

[HTML][HTML] Fibroblast growth factor receptor 4 Gly388Arg polymorphism in Chinese gastric cancer patients

YY Shen, YC Lu, DP Shen, YJ Liu, XY Su… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate the contribution of the fibroblast growth factor receptor 4 (FGFR4)
Gly388Arg polymorphism as a genetic risk factor for gastric cancer (GC) and to investigate …

FGFR4 genetic polymorphisms determine the chemotherapy response of Chinese patients with non-small cell lung cancer

H Fang, G Tian, L Zhou, H Zhou, Y Fang - Acta pharmacologica Sinica, 2013 - nature.com
Aim: To investigate the relationship of fibroblast growth factor receptor 4 (FGFR4) gene
polymorphisms with the response of Chinese patients with non-small cell lung cancer …