The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …

G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

The SLC22 family contains 13 functionally characterized human plasma membrane proteins
each with 12 predicted α-helical transmembrane domains. The family comprises organic …

The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

Dopamine is a biologically active amine synthesized in the central and peripheral nervous
system. This biogenic monoamine acts by activating five types of dopamine receptors (D1 …

All of the components of a complete dopamine system are present within the kidney, where
dopamine acts as a paracrine substance in the control of sodium excretion. Dopamine …

Dopamine plays an important role in the pathogenesis of hypertension by regulating
epithelial sodium transport, vascular smooth muscle contractility and production of reactive …

In addition to its role as an essential neurotransmitter, dopamine serves important
physiologic functions in organs such as the kidney. Although the kidney synthesizes …

The Na/K-ATPase was discovered as an energy transducing ion pump. A major difference
between the Na/K-ATPase and other P-type ATPases is its ability to bind a group of …