Metabolic engineering in food crops to enhance ascorbic acid production: crop biofortification perspectives for human health

S Chaturvedi, S Khan, RK Bhunia, K Kaur… - … and Molecular Biology of …, 2022 - Springer
Ascorbic acid (AsA) also known as vitamin C is considered as an essential micronutrient in
the diet of humans. The human body is unable to synthesize AsA, thus solely dependent on …

Manipulation of ascorbate biosynthetic, recycling, and regulatory pathways for improved abiotic stress tolerance in plants

RC Broad, JP Bonneau, RP Hellens… - International Journal of …, 2020 - mdpi.com
Abiotic stresses, such as drought, salinity, and extreme temperatures, are major limiting
factors in global crop productivity and are predicted to be exacerbated by climate change …

Expression Pattern and Functional Analyses of Arabidopsis Guard Cell-Enriched GDSL Lipases

C Xiao, H Guo, J Tang, J Li, X Yao, H Hu - Frontiers in Plant Science, 2021 - frontiersin.org
There are more than 100 GDSL lipases in Arabidopsis, but only a few members have been
functionally investigated. Moreover, no reports have ever given a comprehensive analysis of …

Gene expression profiling in Rosa roxburghii fruit and overexpressing RrGGP2 in tobacco and tomato indicates the key control point of AsA biosynthesis

Y Yan, Y Liu, M Lu, C Lu, RA Ludlow, M Yang… - Frontiers in Plant …, 2023 - frontiersin.org
Rosa roxburghii Tratt. is an important commercial horticultural crop endemic to China, which
is recognized for its extremely high content of L-ascorbic acid (AsA). To understand the …

Effect of Rice GDP-L-Galactose Phosphorylase Constitutive Overexpression on Ascorbate Concentration, Stress Tolerance, and Iron Bioavailability in Rice

RC Broad, JP Bonneau, JT Beasley, S Roden… - Frontiers in Plant …, 2020 - frontiersin.org
Ascorbate (vitamin C) is an essential multifunctional molecule for both plants and mammals.
In plants, ascorbate is the most abundant water-soluble antioxidant that supports stress …

Overexpression of banana GDP-L-galactose phosphorylase (GGP) modulates the biosynthesis of ascorbic acid in Arabidopsis thaliana

S Chaturvedi, N Thakur, S Khan, MK Sardar… - International Journal of …, 2023 - Elsevier
Abstract l-Ascorbic acid (AsA) is a potent antioxidant and essential micronutrient for the
growth and development of plants and animals. AsA is predominantly synthesized by the …

Characterization of the GGP gene family in potato (Solanum tuberosum L.) and Pepper (Capsicum annuum L.) and its expression analysis under hormonal and …

Z Ding, K Yao, Y Yao, X Pan, L Luo, L Li, C Wang… - Scientific Reports, 2024 - nature.com
GDP-l-galactose phosphorylase (GGP) is a key rate-limiting enzyme in plant ascorbic acid
synthesis, which plays an important role in plant growth and development as well as stress …

Discovery of a conserved translationally repressive upstream open reading frame within the iron-deficiency response regulator IDEF2

O Carey-Fung, JT Beasley, RC Broad, RP Hellens… - BMC Plant …, 2024 - Springer
Abstract Background Iron (Fe) deficiency affects 30–50% of the world's population. Genetic
biofortification of staple crops is a promising strategy for improving human nutrition, but the …

Deciphering the Genomic Characterization of the GGP Gene Family and Expression Verification of CmGGP1 Modulating Ascorbic Acid Biosynthesis in Melon Plants

T Yang, S Amanullah, S Li, P Gao, J Bai, C Li, J Ma… - Antioxidants, 2024 - mdpi.com
Ascorbic acid (AsA), also known as vitamin C, is a well-known antioxidant found in living
entities that plays an essential role in growth and development, as well as in defensive …

Overexpression of RrGGP2 and RrDHAR Increases Ascorbic Acid Content in Tomato

Z Liu, T Rao, RA Ludlow, Y Yan, M Lu, H An - Horticulturae, 2023 - mdpi.com
Ascorbic acid (AsA) is the most abundant antioxidant in plants and is an important nutritional
index for agricultural products. Some plants, such as Rosa roxburghii Tratt., contain …