Orbital neoplasms in adults may be categorized on the basis of location and histologic type.
Imaging features of these lesions often reflect their tissue composition. Cavernous …

Optic pathway gliomas (OPGs) occur in 15%–20% of children with neurofibromatosis type 1
(NF1), leading to visual deficits in fewer than half of these individuals. The goal of …

Although standard chemotherapy remains the mainstay of ONG treatment, newer
molecularly targeted therapies such as mitogen-activated protein kinase kinase inhibitors …

Abstract Neurofibromatosis type 1 (NF1) is a relatively common multisystemic inherited
disease and has been extensively studied by multiple disciplines. Although genetic testing …

Topic Children and adults with neurofibromatosis type 1 (NF1), a common autosomal
dominant condition, manifest a variety of ophthalmologic conditions. Plexiform …

Neurofibromatosis type 1 is an autosomal dominant neurocutaneous disorder affecting 1 in
3000 births. This familial tumor predisposition syndrome is diagnosed clinically and affects …

Abstract Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in
Neurofibromin 1 (NF1). NF1 patients present with a variety of clinical manifestations and are …

Proptosis, the protrusion of the eyeball from the orbit, results from a wide variety of
pathologies that can be vision-or life-threatening. Clinical history, associated physical exam …

OPG may range in their behavior based upon the nature of the tumor (NF-1 or sporadic).
Current guidelines recommend following patients with regular clinical examinations …

Neurofibromatosis 1 is a complex inherited neurocutaneous disease that is often difficult to
diagnose early because of its age-dependent presentation. The diagnosis is also extremely …