[HTML][HTML] Artificial intelligence and statistical methods for stratification and prediction of progression in amyotrophic lateral sclerosis: A systematic review

E Tavazzi, E Longato, M Vettoretti, H Aidos… - Artificial Intelligence in …, 2023 - Elsevier
Abstract Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative
disorder characterised by the progressive loss of motor neurons in the brain and spinal cord …

Machine learning solutions applied to amyotrophic lateral sclerosis prognosis: a review

F Papaiz, MET Dourado Jr, RAM Valentim… - Frontiers in Computer …, 2022 - frontiersin.org
The prognosis of Amyotrophic Lateral Sclerosis (ALS), a complex and rare disease,
represents a challenging and essential task to better comprehend its progression and …

[HTML][HTML] Learning prognostic models using a mixture of biclustering and triclustering: Predicting the need for non-invasive ventilation in Amyotrophic Lateral Sclerosis

DF Soares, R Henriques, M Gromicho… - Journal of Biomedical …, 2022 - Elsevier
Longitudinal cohort studies to study disease progression generally combine temporal
features produced under periodic assessments (clinical follow-up) with static features …

[HTML][HTML] Learning dynamic Bayesian networks from time-dependent and time-independent data: Unraveling disease progression in Amyotrophic Lateral Sclerosis

T Leao, SC Madeira, M Gromicho… - Journal of Biomedical …, 2021 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing patients to
quickly lose motor neurons. The disease is characterized by a fast functional impairment and …

Triclustering-based classification of longitudinal data for prognostic prediction: targeting relevant clinical endpoints in amyotrophic lateral sclerosis

DF Soares, R Henriques, M Gromicho… - Scientific Reports, 2023 - nature.com
This work proposes a new class of explainable prognostic models for longitudinal data
classification using triclusters. A new temporally constrained triclustering algorithm, termed …

Learning prognostic models using disease progression patterns: Predicting the need for non-invasive ventilation in amyotrophic lateral sclerosis

AS Martins, M Gromicho, S Pinto… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
Amyotrophic Lateral Sclerosis is a devastating neurodegenerative disease causing rapid
degeneration of motor neurons and usually leading to death by respiratory failure. Since …

[PDF][PDF] Using wearable and environmental data to improve the prediction of amyotrophic lateral sclerosis and multiple sclerosis progression: an explorative study

E Marinello, A Guazzo, E Longato, E Tavazzi… - CEUR WORKSHOP …, 2024 - ceur-ws.org
Abstract Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS) are chronic
diseases with a severe impact on patients' lives. Both diseases create significant …

[PDF][PDF] Investigating the Impact of Environmental Data on ALS Prognosis with Survival Analysis.

R Branco, DF Soares, AS Martins, JB Valente… - CLEF (Working …, 2023 - ceur-ws.org
Amyotrophic lateral sclerosis (ALS) is characterized by rapid motor neuron degeneration
and subsequent loss of motor function, typically leading to death by respiratory failure. As …

Dynamic Bayesian networks for stratification of disease progression in amyotrophic lateral sclerosis

M Gromicho, T Leão, M Oliveira Santos… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Progression rate is quite variable in amyotrophic lateral sclerosis
(ALS); thus, tools for profiling disease progression are essential for timely interventions. The …

[HTML][HTML] Explainable models of disease progression in ALS: Learning from longitudinal clinical data with recurrent neural networks and deep model explanation

M Müller, M Gromicho, M de Carvalho… - Computer Methods and …, 2021 - Elsevier
Abstract Background and Objectives Deep neural networks recently become a popular tool
in medical research to predict disease progression and unveil its underlying temporal …