[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X Xie, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

Construction of multifunctional wound dressings with their application in chronic wound treatment

L Long, W Liu, C Hu, L Yang, Y Wang - Biomaterials science, 2022 - pubs.rsc.org
As the prevalence of diabetes increases year by year and the aging population continues to
intensify in the world, chronic wounds such as diabetic foot ulcers and pressure ulcers have …

All‐Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity

YJ Fu, YF Shi, LY Wang, YF Zhao, RK Wang… - Advanced …, 2023 - Wiley Online Library
Macrophages are highly heterogeneous and exhibit a diversity of functions and phenotypes.
They can be divided into pro‐inflammatory macrophages (M1) and anti‐inflammatory …

[HTML][HTML] Sustained release of magnesium and zinc ions synergistically accelerates wound healing

F Yang, Y Xue, F Wang, D Guo, Y He, X Zhao, F Yan… - Bioactive Materials, 2023 - Elsevier
Skin wounds are a major medical challenge that threaten human health. Functional
hydrogel dressings demonstrate great potential to promote wound healing. In this study …

Transdermal drug delivery via microneedles to mediate wound microenvironment

R Mo, H Zhang, Y Xu, X Wu, S Wang, Z Dong… - Advanced Drug Delivery …, 2023 - Elsevier
Cutaneous wound healing is a complex process, while modulating the wound
microenvironment has become an essential therapeutic goal. In clinics, advanced dressings …

Layered GelMA/PEGDA hydrogel microneedle patch as an intradermal delivery system for hypertrophic scar treatment

Z Chen, X Hu, Z Lin, H Mao, Z Qiu… - … Applied Materials & …, 2023 - ACS Publications
Hypertrophic scar (HS) is an unfavorable skin disorder that typically develops after trauma,
burn injury, or surgical procedures and causes numerous physical and psychological issues …

[HTML][HTML] Human urine-derived stem cell exosomes delivered via injectable GelMA templated hydrogel accelerate bone regeneration

W Lu, M Zeng, W Liu, T Ma, X Fan, H Li, Y Wang… - Materials Today Bio, 2023 - Elsevier
The key to critical bone regeneration in tissue engineering relies on an ideal bio-scaffold
coated with a controlled release of growth factors. Gelatin methacrylate (GelMA) and …

MiR‐141‐3p‐Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment

S Meng, Q Wei, S Chen, X Liu, S Cui, Q Huang, Z Chu… - Small, 2024 - Wiley Online Library
Hypertrophic scar (HS) is a common fibroproliferative disease caused by abnormal wound
healing after deep skin injury. However, the existing approaches have unsatisfactory …

Smart microneedle patches for wound healing and management

F Hu, Q Gao, J Liu, W Chen, C Zheng, Q Bai… - Journal of Materials …, 2023 - pubs.rsc.org
The number of patients with non-healing wounds is generally increasing globally, placing a
huge social and economic burden on every country. The complexity of the wound-healing …

Composite microneedles loaded with Astragalus membranaceus polysaccharide nanoparticles promote wound healing by curbing the ROS/NF-κB pathway to …

X Liu, C Guo, W Yang, W Wang, N Diao, M Cao… - Carbohydrate …, 2024 - Elsevier
The healing of chronic diabetic wounds remains a formidable challenge in modern times. In
this study, a novel traditional Chinese medicine microneedle patch was designed based on …