Tissue development occurs through a complex interplay between many individual cells. Yet,
the fundamental question of how collective tissue behavior emerges from heterogeneous …

Stem cells are subject to continuous regulation to ensure that the correct balance between
stem cell differentiation and self-renewal is maintained. The dynamic and ongoing nature of …

Anatomic visualization and molecular typing of metastatic regional lymph nodes in breast
cancer patients are a serious clinical challenge in modern oncology. According to the results …

Most hematological malignancies are associated with reduced expression of one or more
components of the Endosomal Sorting Complex Required for Transport (ESCRT). However …

The current immunooncology artificially ignores the connection with lymphopoiesis, though
is only its derivative. Hematopoietic stem cells (HSC) provide physiological regeneration of …

The Drosophila lymph gland houses blood progenitors that give rise to myeloid-like blood
cells. Initially, blood progenitors proliferate, but later become quiescent to maintain …

Drosophila larval hematopoiesis takes place at the lymph gland, where blood cell
progenitors differentiate into two possible cell types: plasmatocytes, analogous to …

Модельный организм–плодовая мушка Drosophila melanogaster–занял одно из
ведущих мест в современных биологических исследованиях. Генетическая модельная …

Hematopoiesis is a process where blood cells with distinct functions are produced from
hematopoietic stem cells. This process is regulated, both biochemically and biophysically …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor and is
comprised of transcriptionally heterogeneous cells and a complex microenvironment …