Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary …

D Aradi, A Kirtane, L Bonello, PA Gurbel… - European heart …, 2015 - academic.oup.com
Aims Although platelet reactivity during P2Y12-inhibitors is associated with stent thrombosis
(ST) and bleeding, standardized and clinically validated thresholds for accurate risk …

Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate

L Bonello, US Tantry, R Marcucci, R Blindt… - Journal of the American …, 2010 - jacc.org
The addition of clopidogrel to aspirin treatment reduces ischemic events in a wide range of
patients with cardiovascular disease. However, recurrent ischemic event occurrence during …

Standard-vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial

MJ Price, PB Berger, PS Teirstein, JF Tanguay… - Jama, 2011 - jamanetwork.com
Context High platelet reactivity while receiving clopidogrel has been linked to cardiovascular
events after percutaneous coronary intervention (PCI), but a treatment strategy for this issue …

Point-of-care testing in coagulation

EM Van Cott - Clinics in laboratory medicine, 2009 - labmed.theclinics.com
Point-of-care (POC) assays are available for a variety of coagulation tests. These assays are
generally simple to perform and have a more rapid turnaround time than their central …

Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation

NJ Breet, JW van Werkum, HJ Bouman, JC Kelder… - Jama, 2010 - jamanetwork.com
Context High on-treatment platelet reactivity is associated with atherothrombotic events
following coronary stent implantation. Objective To evaluate the capability of multiple platelet …

Coronary stents: current status

S Garg, PW Serruys - Journal of the American College of Cardiology, 2010 - jacc.org
Coronary artery stents revolutionized the practice of interventional cardiology after they were
first introduced in the mid-1980s. Since then, there have been significant developments in …

Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention: a collaborative meta-analysis of individual participant data

SS Brar, J Ten Berg, R Marcucci, MJ Price… - Journal of the American …, 2011 - jacc.org
Objectives: The purpose of the study was to systematically evaluate the significance of
platelet reactivity on clopidogrel treatment on adverse cardiovascular events using a …

Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: a time-dependent analysis of the Gauging Responsiveness with a VerifyNow …

MJ Price, DJ Angiolillo, PS Teirstein, E Lillie… - Circulation, 2011 - Am Heart Assoc
Background—In the Gauging Responsiveness With A VerifyNow P2Y12 Assay: Impact on
Thrombosis and Safety (GRAVITAS) trial, 6 months of high-dose clopidogrel did not reduce …

Platelet reactivity after clopidogrel treatment assessed with point-of-care analysis and early drug-eluting stent thrombosis

D Sibbing, S Braun, T Morath, J Mehilli, W Vogt… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of this prospective trial was to assess whether platelet reactivity to
clopidogrel assessed with multiple electrode platelet aggregometry (MEA) correlates with …

Maintenance of platelet inhibition during antiplatelet therapy

LR Chen, S Skerjanec, D Bell, J Prats… - US Patent 10,022,391, 2018 - Google Patents
Related US Application Data 2 () 13/() 19 () 265 A 1 7/20 13 Arculus-Meanwell et al. 2 ()
13/() 3 () 3477 A 1 1 1/2 () 13 (Chen et g1,(63) Continuation of application No. 14/269,429 …