A unified hypothesis of SUDEP: Seizure‐induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and …

CL Faingold, HJ Feng - Epilepsia, 2023 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in people with
epilepsy (PWE). Postictal apnea leading to cardiac arrest is the most common sequence of …

Sudden unexpected death in epilepsy

GF Buchanan, ATN Maciel… - Current opinion in …, 2023 - journals.lww.com
Sudden unexpected death in epilepsy : Current Opinion in Neurology Sudden unexpected
death in epilepsy : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …

Failure to breathe persists without air hunger or alarm following amygdala seizures

GIS Harmata, AE Rhone, CK Kovach, S Kumar… - JCI insight, 2023 - insight.jci.org
Sudden unexpected death in epilepsy (SUDEP) accounts for 10%–50% of all deaths in
individuals with medically refractory epilepsy (1). Accumulating evidence indicates that the …

[HTML][HTML] The cerebellum's understated role and influences in the epilepsies

ML Streng, JM Froula, E Krook-Magnuson - Neurobiology of disease, 2023 - Elsevier
Approximately 1 in 26 people will develop epilepsy in their lifetime, but current treatment
options leave as many as half of all epilepsy patients with uncontrolled seizures. In addition …

Forebrain control of breathing: anatomy and potential functions

KM Schottelkotte, SA Crone - Frontiers in Neurology, 2022 - frontiersin.org
The forebrain plays important roles in many critical functions, including the control of
breathing. We propose that the forebrain is important for ensuring that breathing matches …

Sudden unexpected death in epilepsy

D Friedman - Current Opinion in Neurology, 2022 - journals.lww.com
Sudden unexpected death in epilepsy : Current Opinion in Neurology Sudden unexpected
death in epilepsy : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …

Peri-ictal activation of dorsomedial dorsal raphe serotonin neurons reduces mortality associated with maximal electroshock seizures

AN Petrucci, AR Jones, BL Kreitlow… - Brain …, 2024 - academic.oup.com
Over one-third of patients with epilepsy will develop refractory epilepsy and continue to
experience seizures despite medical treatment. These patients are at the greatest risk for …

Sudden unexpected death in epilepsy is prevented by blocking postictal hypoxia

AG George, JS Farrell, R Colangeli, AK Wall… - …, 2023 - Elsevier
Epilepsy is at times a fatal disease. Sudden unexpected death in epilepsy (SUDEP) is the
leading cause of epilepsy-related mortality in people with intractable epilepsy and is defined …

Neuronal plasticity contributes to postictal death

A Brodovskaya, H Sun, N Adotevi, IC Wenker… - Progress in …, 2023 - Elsevier
Repeated generalized tonic-clonic seizures (GTCSs) are the most critical risk factor for
sudden unexpected death in epilepsy (SUDEP). GTCSs can cause fatal apnea. We …

The bidirectional relationship between the cerebellum and seizure networks: a double-edged sword

ML Streng - Current Opinion in Behavioral Sciences, 2023 - Elsevier
Highlights•The cerebellum may be a potential target for therapeutic intervention in
epilepsy.•Modulation of cerebellar neurons can attenuate seizures in animal models of …