Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence
of calcification may change portions of the arterial conduit to a noncompliant structure …

Rationale: Matrix vesicles (MVs), secreted by vascular smooth muscle cells (VSMCs), form
the first nidus for mineralization and fetuin-A, a potent circulating inhibitor of calcification, is …

It is more than 50years since the lysosome was discovered. Since then its hydrolytic
machinery, including proteases and other hydrolases, has been fairly well identified and …

AGE/RAGE signaling has been a well‐studied cascade in many different disease states,
particularly diabetes. Due to the complex nature of the receptor and multiple intersecting …

Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

A high prevalence of vascular calcification (VC) and a high incidence of cardiovascular
events are two key complications of chronic kidney disease. Since most observational …

Combined results are reported from searches for the standard model Higgs boson in proton–
proton collisions at s= 7 TeV in five Higgs boson decay modes: γγ, bb, ττ, WW, and ZZ. The …

Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have
significant cardiovascular morbidity and mortality that is in part due to the development of …

Fetuin-A is a heterodimeric plasma glycoprotein containing an A-chain of 282 amino acids
and a B-chain of 27 amino acid residues linked by a single inter-disulfide bond. It is …