Intracameral drug delivery: a review of agents, indications, and outcomes

M Gautam, R Gupta, P Singh, V Verma… - Journal of Ocular …, 2023 - liebertpub.com
An intracameral (IC) injection directly delivers the drug into the anterior chamber of the eye.
This targeted drug delivery technique overcomes the ocular barriers and offers a high …

[HTML][HTML] Lipid-nanoparticles-based co-delivery of black phosphorus quantum dots and melphalan by photothermal therapy combined with chemotherapy for …

S Wang, P Wei, Y Zhang, S Zhang - Polymer Testing, 2023 - Elsevier
Melphalan is an efficient chemotherapeutic agent for retinoblastoma (RB) in clinical practice.
However, the problems of drug resistance and poor prognosis caused by long-term …

Publication trends of research on retinoblastoma during 2001–2021: a 20-year bibliometric analysis

X Gu, M Xie, R Jia, S Ge - Frontiers in medicine, 2021 - frontiersin.org
Background: Retinoblastoma is the most common primary intraocular malignancy of
childhood. Despite high survival and eye salvage as the result of various types of therapies …

Retinoblastoma: An update on genetic origin, classification, conventional to next-generation treatment strategies

A Pareek, D Kumar, A Pareek, MM Gupta, P Jeandet… - Heliyon, 2024 - cell.com
The most prevalent paediatric vision-threatening medical condition, retinoblastoma (RB),
has been a global concern for a long time. Several conventional therapies, such as systemic …

Topical instillation of cell-penetrating peptide-conjugated melphalan blocks metastases of retinoblastoma

K Jiang, X Fan, Y Hu, S Yao, Y Liu, C Zhan, W Lu… - Biomaterials, 2022 - Elsevier
Retinoblastoma is the most common primary intraocular malignancy in infancy with a
metastases-related death risk. However, a safe and convenient treatment without …

Safety and efficacy of intravitreal chemotherapy (melphalan) to treat vitreous seeds in retinoblastoma

YA Yousef, M Al Jboor, M Mohammad… - Frontiers in …, 2021 - frontiersin.org
Background: Active vitreous seeds in eyes with retinoblastoma (Rb) adversely affects the
treatment outcome. This study aimed to investigate the safety and efficacy of intravitreal …

Retinoblastoma and uveal melanoma in Jordan: incidence, demographics, and survival (2011-2020)

YA Yousef, M Mohammad, I Al-Nawaiseh… - Ophthalmic …, 2023 - Taylor & Francis
Purpose We present an epidemiologic analysis of retinoblastoma (RB) and uveal melanoma
(UM) in Jordan to aid national strategies for improved ocular cancer surveillance and …

Ocular Survival Following Intravitreal Melphalan as Adjuvant Treatment for Vitreous Retinoblastoma Seeding

G Alahmadi, AMY Maktabi, G Sesma… - Clinical …, 2023 - Taylor & Francis
Purpose To evaluate the efficacy of intravitreal chemotherapy for vitreous seeding in patients
with retinoblastoma (Rb). Design Retrospective, single-arm cohort study. Methods This study …

Retinoblastoma seeds: impact on American Joint Committee on Cancer clinical staging

AS Tomar, PT Finger, B Gallie, T Kivelä… - British Journal of …, 2023 - bjo.bmj.com
Aim To investigate whether the American Joint Committee on Cancer (AJCC) clinical
category cT2b needs to be subclassified by the type and distribution of retinoblastoma (RB) …

Causes of death and survival analysis for patients with retinoblastoma in Jordan

T Bilbeisi, R Almasry, M Obeidat, M Mohammad… - Frontiers in …, 2023 - frontiersin.org
Purpose To analyze causes and prognostic factors for death among Retinoblastoma (Rb)
patients treated at a single specialized tertiary cancer center in Jordan. Methods We …