Tissue engineering and regenerative medicine: achievements, future, and sustainability in Asia

F Han, J Wang, L Ding, Y Hu, W Li, Z Yuan… - … in bioengineering and …, 2020 - frontiersin.org
Exploring innovative solutions to improve the healthcare of the aging and diseased
population continues to be a global challenge. Among a number of strategies toward this …

Mesenchymal stem cells empowering tendon regenerative therapies

R Costa-Almeida, I Calejo, ME Gomes - International journal of molecular …, 2019 - mdpi.com
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …

Bone marrow mesenchymal stem cell-derived exosomes promote tendon regeneration by facilitating the proliferation and migration of endogenous tendon stem …

H Yu, J Cheng, W Shi, B Ren, F Zhao, Y Shi, P Yang… - Acta biomaterialia, 2020 - Elsevier
Mesenchymal stem cells (MSCs)-derived exosomes are being increasingly focused as the
new biological pro-regenerative therapeutic agents for various types of tissue injury. Here …

Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant periostin

Y Wang, S Jin, D Luo, D He, C Shi, L Zhu… - Nature …, 2021 - nature.com
Tendon injuries disrupt the balance between stability and mobility, causing compromised
functions and disabilities. The regeneration of mature, functional tendons remains a clinical …

Recent advances in tendon tissue engineering strategy

C Ning, P Li, C Gao, L Fu, Z Liao, G Tian… - … in Bioengineering and …, 2023 - frontiersin.org
Tendon injuries often result in significant pain and disability and impose severe clinical and
financial burdens on our society. Despite considerable achievements in the field of …

[HTML][HTML] The tendon microenvironment: Engineered in vitro models to study cellular crosstalk

M Gomez-Florit, CJ Labrador-Rached… - Advanced Drug Delivery …, 2022 - Elsevier
Tendinopathy is a multi-faceted pathology characterized by alterations in tendon
microstructure, cellularity and collagen composition. Challenged by the possibility of …

Adipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3

H Liu, M Zhang, M Shi, T Zhang, W Lu, S Yang… - Stem Cell Research & …, 2021 - Springer
Background The use of adipose-derived mesenchymal stromal cell-derived exosomes
(ADSC-Exos) may become a new therapeutic method in biomedicine owing to their …

Tendon stem progenitor cells: Understanding the biology to inform therapeutic strategies for tendon repair

B Walia, AH Huang - Journal of Orthopaedic Research®, 2019 - Wiley Online Library
Tendon and ligament injuries are a leading cause of healthcare visits with significant impact
in terms of economic cost and reduced quality of life. To date, reparative strategies remain …

Mussel‐Derived Bioadaptive Artificial Tendon Facilitates the Cell Proliferation and Tenogenesis to Promote Tendon Functional Reconstruction

X Wang, K Xu, L Mu, X Zhang, G Huang… - Advanced …, 2023 - Wiley Online Library
Tendon injuries range from acute‐related trauma to chronic‐related injuries are prevalent
and bring substantial pain, functional loss, and even disability to the patients. The …

Synergistic effects of mechanical stimulation and crimped topography to stimulate natural collagen development for tendon engineering

Z Chen, B Zhou, X Wang, G Zhou, W Zhang, B Yi… - Acta biomaterialia, 2022 - Elsevier
Suitable scaffold structures and mechanical loading are essential for functional tendon
engineering. However, the bipolar fibril structure of native tendon collagen is yet to be …