Anticancer mechanisms of cannabinoids
In addition to the well-known palliative effects of cannabinoids on some cancer-associated
symptoms, a large body of evidence shows that these molecules can decrease tumour …
symptoms, a large body of evidence shows that these molecules can decrease tumour …
Towards the use of cannabinoids as antitumour agents
Various reports have shown that cannabinoids (the active components of marijuana and
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …
Cannabinoids as novel anti-inflammatory drugs
P Nagarkatti, R Pandey, SA Rieder… - Future medicinal …, 2009 - Taylor & Francis
Cannabinoids are a group of compounds that mediate their effects through cannabinoid
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …
The endocannabinoid system and its therapeutic exploitation
The term'endocannabinoid'—originally coined in the mid-1990s after the discovery of
membrane receptors for the psychoactive principle in Cannabis, Δ9-tetrahydrocannabinol …
membrane receptors for the psychoactive principle in Cannabis, Δ9-tetrahydrocannabinol …
Cannabinoids: potential anticancer agents
M Guzman - Nature reviews cancer, 2003 - nature.com
Cannabinoids—the active components of Cannabis sativa and their derivatives—exert
palliative effects in cancer patients by preventing nausea, vomiting and pain and by …
palliative effects in cancer patients by preventing nausea, vomiting and pain and by …
[HTML][HTML] Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
ML Casanova, C Blázquez… - The Journal of …, 2003 - Am Soc Clin Investig
Nonmelanoma skin cancer is one of the most common malignancies in humans. Different
therapeutic strategies for the treatment of these tumors are currently being investigated …
therapeutic strategies for the treatment of these tumors are currently being investigated …
Non-alcoholic fatty liver disease pathogenesis: the present and the future
Non-alcoholic fatty liver disease is the clinical hepatic expression of metabolic syndrome.
The prevalence of non-alcoholic fatty liver disease is around 20–30%, and with a rapid …
The prevalence of non-alcoholic fatty liver disease is around 20–30%, and with a rapid …
Antifibrogenic role of the cannabinoid receptor CB2 in the liver
B Julien, P Grenard, F Teixeira-Clerc, JT Van Nhieu… - Gastroenterology, 2005 - Elsevier
Background & Aims: Hepatic myofibroblasts are central for the development of liver fibrosis
associated with chronic liver diseases, and blocking their accumulation may prevent …
associated with chronic liver diseases, and blocking their accumulation may prevent …
Cannabinoid receptor expression in non-small cell lung cancer. Effectiveness of tetrahydrocannabinol and cannabidiol inhibiting cell proliferation and epithelial …
L Milian, M Mata, J Alcacer, M Oliver, M Sancho-Tello… - PLoS one, 2020 - journals.plos.org
Background/Objective Patients with non-small cell lung cancer (NSCLC) develop resistance
to antitumor agents by mechanisms that involve the epithelial-to-mesenchymal transition …
to antitumor agents by mechanisms that involve the epithelial-to-mesenchymal transition …
Non‐THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro‐apoptotic effects and underlying mechanisms
L De Petrocellis, A Ligresti… - British journal of …, 2013 - Wiley Online Library
BACKGROUND AND PURPOSE Cannabinoid receptor activation induces prostate
carcinoma cell (PCC) apoptosis, but cannabinoids other than Δ9‐tetrahydrocannabinol …
carcinoma cell (PCC) apoptosis, but cannabinoids other than Δ9‐tetrahydrocannabinol …