Machine learning for synthetic data generation: a review

Y Lu, M Shen, H Wang, X Wang, C van Rechem… - arXiv preprint arXiv …, 2023 - arxiv.org
Machine learning heavily relies on data, but real-world applications often encounter various
data-related issues. These include data of poor quality, insufficient data points leading to …

Trialbench: Multi-modal artificial intelligence-ready clinical trial datasets

J Chen, Y Hu, Y Wang, Y Lu, X Cao, M Lin, H Xu… - arXiv preprint arXiv …, 2024 - arxiv.org
Clinical trials are pivotal for developing new medical treatments, yet they typically pose
some risks such as patient mortality, adverse events, and enrollment failure that waste …

Uncertainty quantification on clinical trial outcome prediction

T Chen, N Hao, Y Lu, C Van Rechem - arXiv preprint arXiv:2401.03482, 2024 - arxiv.org
The importance of uncertainty quantification is increasingly recognized in the diverse field of
machine learning. Accurately assessing model prediction uncertainty can help provide …

Drugclip: Contrastive drug-disease interaction for drug repurposing

Y Lu, Y Hu, C Li - arXiv preprint arXiv:2407.02265, 2024 - arxiv.org
Bringing a novel drug from the original idea to market typically requires more than ten years
and billions of dollars. To alleviate the heavy burden, a natural idea is to reuse the approved …

TrialEnroll: Predicting Clinical Trial Enrollment Success with Deep & Cross Network and Large Language Models

L Yue, S Xing, J Chen, T Fu - arXiv preprint arXiv:2407.13115, 2024 - arxiv.org
Clinical trials need to recruit a sufficient number of volunteer patients to demonstrate the
statistical power of the treatment (eg, a new drug) in curing a certain disease. Clinical trial …

Quantum-machine-assisted Drug Discovery: Survey and Perspective

Y Zhou, J Chen, W Li, J Cheng, G Karemore… - arXiv preprint arXiv …, 2024 - arxiv.org
Drug discovery and development is a highly complex and costly endeavor, typically
requiring over a decade and substantial financial investment to bring a new drug to market …

DrugAgent: Explainable Drug Repurposing Agent with Large Language Model-based Reasoning

Y Inoue, T Song, T Fu - arXiv preprint arXiv:2408.13378, 2024 - arxiv.org
Drug repurposing offers a promising avenue for accelerating drug development by
identifying new therapeutic potentials of existing drugs. In this paper, we propose a multi …

GenoCraft: A Comprehensive, User-Friendly Web-Based Platform for High-Throughput Omics Data Analysis and Visualization

Y Lu, M Shen, Y Zhao, C Li, F Meng, X Wang… - arXiv preprint arXiv …, 2023 - arxiv.org
The surge in high-throughput omics data has reshaped the landscape of biological
research, underlining the need for powerful, user-friendly data analysis and interpretation …

Accelerated Markov Chain Monte Carlo Using Adaptive Weighting Scheme

Y Wang, W Chen, S Shan - arXiv preprint arXiv:2408.12888, 2024 - arxiv.org
Gibbs sampling is one of the most commonly used Markov Chain Monte Carlo (MCMC)
algorithms due to its simplicity and efficiency. It cycles through the latent variables, sampling …

Artificial Intelligence-Aided Digital Twin Design: A Systematic Review

N Hao, Y Li, K Liu, S Liu, Y Lu, B Xu, C Li, J Chen… - 2024 - preprints.org
Digital twin technology, a cutting-edge approach that creates dynamic digital replicas of
physical systems, is increasingly integral to various industrial applications. However, the …