[HTML][HTML] Aspergillus derived mycotoxins in food and the environment: Prevalence, detection, and toxicity

V Navale, KR Vamkudoth, S Ajmera, V Dhuri - Toxicology reports, 2021 - Elsevier
Aspergillus species are the paramount ubiquitous fungi that contaminate various food
substrates and produce biochemicals known as mycotoxins. Aflatoxins (AFTs), ochratoxin A …

Recent advances in Pd-catalyzed asymmetric cyclization reactions

B Xu, Q Wang, C Fang, ZM Zhang… - Chemical Society Reviews, 2024 - pubs.rsc.org
Over the past few decades, there have been major developments in transition metal-
catalyzed asymmetric cyclization reactions, enabling the convenient access to a wide …

Forty years after “Heterodiene syntheses with α, β-unsaturated carbonyl compounds”: enantioselective syntheses of 3, 4-dihydropyran derivatives

G Desimoni, G Faita, P Quadrelli - Chemical reviews, 2018 - ACS Publications
This review is focused on the enantioselective synthesis of 3, 4-dihydropyran derivatives,
whose importance as chiral building blocks in the synthesis of bioactive molecules and …

Asymmetric Pd (II)‐Catalyzed C− O, C− N, C− C Bond Formation Using Alkenes as Substrates: Insight into Recent Enantioselective Developments

S Giofrè, L Molteni, EM Beccalli - European Journal of Organic …, 2023 - Wiley Online Library
This Review summarizes the advances in the catalytic enantioselective mono‐and
difunctionalization of alkenes, highlighting the fundamental role of ligands. Several types of …

A Common C2‐Symmetric 2,2'‐Biphenol Building Block and its Application in the Synthesis of (+)‐di‐epi‐Gonytolide A

J Greb, T Drennhaus, MKT Klischan… - … A European Journal, 2023 - Wiley Online Library
A variety of biaryl polyketides exhibit remarkable bioactivities. However, their synthetic
accessibility is often challenging. Herein, the enantioselective preparation and synthetic …

Fungal anticancer metabolites: synthesis towards drug discovery

M Barbero, E Artuso, C Prandi - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: Fungi are a well-known and valuable source of compounds of therapeutic
relevance, in particular of novel anticancer compounds. Although seldom obtainable …

Total synthesis and structural determination of the dimeric tetrahydroxanthone ascherxanthone A

Z Xiao, Y Li, S Gao - Organic letters, 2017 - ACS Publications
The first total synthesis of the dimeric tetrahydroxanthone ascherxanthone A has been
accomplished. This synthetic strategy features (1) enantioselective intramolecular allylic C …

[图书][B] Asymmetric synthesis of drugs and natural products

A Nag - 2018 - books.google.com
This book focuses on different techniques of asymmetric synthesis of important compounds,
such as drugs and natural products. It gives insightful information on recent asymmetric …

Enantioselective total synthesis of parnafungin A1 and 10a-epi-hirtusneanine

J Sun, W Gu, H Yang, W Tang - Chemical Science, 2021 - pubs.rsc.org
The first and enantioselective total synthesis of the heterodimeric biaryl antifungal natural
product parnafungin A1 as well as complex biaryl tetrahydroxanthone 10a-epi-hirtusneanine …

Secalonic acid-F, a novel mycotoxin, represses the progression of hepatocellular carcinoma via MARCH1 regulation of the PI3K/AKT/β-catenin signaling pathway

L Xie, M Li, D Liu, X Wang, P Wang, H Dai, W Yang… - Molecules, 2019 - mdpi.com
Liver cancer is a very common and significant health problem. Therefore, powerful
molecular targeting agents are urgently needed. Previously, we demonstrated that secalonic …