Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Role of nitric oxide in the cardiovascular and renal systems

A Ahmad, SK Dempsey, Z Daneva, M Azam… - International journal of …, 2018 - mdpi.com
The gasotransmitters are a family of gaseous signaling molecules which are produced
endogenously and act at specific receptors to play imperative roles in physiologic and …

Carbon monoxide, hydrogen sulfide, and nitric oxide as signaling molecules in the gastrointestinal tract

G Farrugia, JH Szurszewski - Gastroenterology, 2014 - Elsevier
Carbon monoxide (CO) and hydrogen sulfide (H 2 S) used to be thought of simply as lethal
and (for H 2 S) smelly gaseous molecules; now they are known to have important signaling …

Hydrogen sulfide signaling in the gastrointestinal tract

DR Linden - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: The current literature regarding the effects of the gaseous signal molecule
hydrogen sulfide (H2S) in the gastrointestinal system is reviewed. Bacterial, host and …

Hydrogen sulfide exposure induces jejunum injury via CYP450s/ROS pathway in broilers

S Zheng, X Jin, M Chen, Q Shi, H Zhang, S Xu - Chemosphere, 2019 - Elsevier
Hydrogen sulfide (H 2 S) is generally recognized as a highly poisonous environmental and
industrial pollutant. Previous toxicological studies of H 2 S are mainly focused on the …

The therapeutic potential of hydrogen sulfide: separating hype from hope

KR Olson - American Journal of Physiology-Regulatory …, 2011 - journals.physiology.org
Hydrogen sulfide (H2S) has become the hot new signaling molecule that seemingly affects
all organ systems and biological processes in which it has been investigated. It has also …

cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation

M Bucci, A Papapetropoulos, V Vellecco, Z Zhou… - PloS one, 2012 - journals.plos.org
A growing body of evidence suggests that hydrogen sulfide (H2S) is a signaling molecule in
mammalian cells. In the cardiovascular system, H2S enhances vasodilation and …

Hydrogen sulfide inhibits proliferation and release of IL-8 from human airway smooth muscle cells

MM Perry, CK Hui, M Whiteman, ME Wood… - American journal of …, 2011 - atsjournals.org
Hydrogen sulfide (H2S) is synthesized intracellularly by the enzymes cystathionine-γ-lyase
and cystathionine-β-synthase (CBS), and is proposed to be a gasotransmitter with effects in …

Role of cGMP in hydrogen sulfide signaling

SI Bibli, G Yang, Z Zhou, R Wang, S Topouzis… - Nitric Oxide, 2015 - Elsevier
The importance of hydrogen sulfide (H 2 S) in physiology and disease is being increasingly
recognized in recent years. Unlike nitric oxide (NO) that signals mainly through soluble …

Hydrogen sulphide inhibits Ca2+ release through InsP3 receptors and relaxes airway smooth muscle

I Castro‐Piedras, JF Perez‐Zoghbi - The Journal of physiology, 2013 - Wiley Online Library
Key points• The novel signalling molecule hydrogen sulphide (H2S) regulates diverse cell
physiological processes in several organs and systems including airway smooth muscle …