Simple Summary Cancer cells in solid tumors often experience lack of oxygen (hypoxia),
which they overcome with the help of hypoxia inducible transcription factors (HIFs). When …

Hypoxia inducible factor-1 (HIF-1), a dimeric transcription factor of the bHLH-PAS family, is
comprised of HIF-1α, which is inducible by hypoxia and ARNT or HIF-1β, which is …

Nitric oxide (NO) is a membrane-permeable signaling molecule that is constantly produced,
transferred, and consumed in vivo. NO participates and plays important roles in multiple …

The aryl hydrocarbon receptor (AhR) heterodimerizes with the aryl hydrocarbon receptor
nuclear translocator (Arnt) for transcriptional regulation. We generated three N-terminal …

Dimerization of hypoxia-inducible factor-1 beta (HIF-1β)[aryl hydrocarbon receptor nuclear
translocator (ARNT)] with HIF-1α is involved in various aspects of cancer biology, including …

The heterodimeric hypoxia inducible factor-1 (HIF-1) complex is composed of the hypoxia
inducible factor-1 alpha (HIF-1α) and the aryl hydrocarbon receptor nuclear translocator …

Reduced oxygen availability (hypoxia) is a characteristic of many disorders including
cancer. Central components of the systemic and cellular response to hypoxia are the …

摘要目的: 探讨芳香烃受体(aryl hydrocarbon receptor, AhR) 在过氧化氢(H2O2)
诱导的人脐静脉内皮细胞(HUVECs) 衰老模型中表达的变化情况及其对血管生成相关因子表达 …

The aryl hydrocarbon receptor (AhR) heterodimerizes with the aryl hydrocarbon receptor
nuclear translocator (Arnt) for transcriptional regulation. We generated three N-terminal …

abstract The heterodimeric hypoxia inducible fact or-1 (HIF-1) complex is compose d of the
hypoxia inducible factor-1 alpha (HIF-1a) and the aryl hydrocarbon receptor nuclear …