Bacterial defences: mechanisms, evolution and antimicrobial resistance

WPJ Smith, BR Wucher, CD Nadell… - Nature Reviews …, 2023 - nature.com
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

Environmental factors influencing the development and spread of antibiotic resistance

J Bengtsson-Palme, E Kristiansson… - FEMS microbiology …, 2018 - academic.oup.com
Antibiotic resistance and its wider implications present us with a growing healthcare crisis.
Recent research points to the environment as an important component for the transmission …

Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics

D Lebeaux, JM Ghigo, C Beloin - Microbiology and Molecular …, 2014 - Am Soc Microbiol
Surface-associated microbial communities, called biofilms, are present in all environments.
Although biofilms play an important positive role in a variety of ecosystems, they also have …

Microbiological effects of sublethal levels of antibiotics

DI Andersson, D Hughes - Nature Reviews Microbiology, 2014 - nature.com
The widespread use of antibiotics results in the generation of antibiotic concentration
gradients in humans, livestock and the environment. Thus, bacteria are frequently exposed …

Integrons: past, present, and future

MR Gillings - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

Antimicrobial use in aquaculture re‐examined: its relevance to antimicrobial resistance and to animal and human health

FC Cabello, HP Godfrey, A Tomova… - Environmental …, 2013 - Wiley Online Library
The worldwide growth of aquaculture has been accompanied by a rapid increase in
therapeutic and prophylactic usage of antimicrobials including those important in human …

SOS, the formidable strategy of bacteria against aggressions

Z Baharoglu, D Mazel - FEMS microbiology reviews, 2014 - academic.oup.com
The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …

Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics

J Bengtsson-Palme, R Hammaren, C Pal… - Science of the Total …, 2016 - Elsevier
Sewage treatment plants (STPs) have repeatedly been suggested as “hotspots” for the
emergence and dissemination of antibiotic-resistant bacteria. A critical question still …

Bacterial stress responses as potential targets in overcoming antibiotic resistance

J Dawan, J Ahn - Microorganisms, 2022 - mdpi.com
Bacteria can be adapted to adverse and detrimental conditions that induce general and
specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative …

Antibiotics and antibiotic resistance: a bitter fight against evolution

A Rodríguez-Rojas, J Rodríguez-Beltrán… - International Journal of …, 2013 - Elsevier
One of the most terrible consequences of Darwinian evolution is arguably the emergence
and spread of antibiotic resistance, which is becoming a serious menace to modern …