Confocal endomicroscopy: instrumentation and medical applications

JM Jabbour, MA Saldua, JN Bixler… - Annals of biomedical …, 2012 - Springer
Advances in fiber optic technology and miniaturized optics and mechanics have propelled
confocal endomicroscopy into the clinical realm. This high resolution, non-invasive imaging …

Confocal microscopy: Imaging cervical precancerous lesions

K Carlson, I Pavlova, T Collier, M Descour, M Follen… - Gynecologic …, 2005 - Elsevier
OBJECTIVES.: We explore the clinical potential of reflectance and fluorescence confocal
microscopy to image the morphologic and biochemical changes associated with precancer …

[HTML][HTML] A confocal endoscope for cellular imaging

J Wang, M Yang, L Yang, Y Zhang, J Yuan, Q Liu… - Engineering, 2015 - Elsevier
Since its inception, endoscopy has aimed to establish an immediate diagnosis that is
virtually consistent with a histologic diagnosis. In the past decade, confocal laser scanning …

Single fiber confocal microscope with a two-axis gimbaled MEMS scanner for cellular imaging

KC Maitland, HJ Shin, H Ra, D Lee, O Solgaard… - Optics express, 2006 - opg.optica.org
We present a single fiber reflectance confocal microscope with a two dimensional MEMS
gimbaled scanner. Achieved lateral and axial resolutions are 0.82 μm and 13 μm …

Integrated semiconductor optical sensors for cellular and neural imaging

O Levi, TT Lee, MM Lee, SJ Smith, JS Harris - Applied optics, 2007 - opg.optica.org
We review integrated optical sensors for functional brain imaging, localized index-of-
refraction sensing as part of a lab-on-a-chip, and in vivo continuous monitoring of tumor and …

Five-lens, easy-to-implement miniature objective for a fluorescence confocal microendoscope

L Yang, J Wang, G Tian, J Yuan, Q Liu, L Fu - Optics Express, 2016 - opg.optica.org
A fluorescence confocal microendoscope requires a high-performance miniature objective.
We present a miniature objective comprising four glass lenses and one plastic aspheric …

500 μm field-of-view probe-based confocal microendoscope for large-area visualization in the gastrointestinal tract

H Li, Z Hao, J Huang, T Lu, Q Liu, L Fu - Photonics Research, 2021 - opg.optica.org
Rapid large-area tissue imaging at the cellular resolution is important for clinical diagnosis.
We present a probe-based confocal microendoscope (pCM) with a field-of-view (FOV) …

High numerical aperture microendoscope objective for a fiber confocal reflectance microscope

RT Kester, TS Tkaczyk, MR Descour, T Christenson… - Optics express, 2007 - opg.optica.org
A disposable high numerical aperture microendoscope objective has been designed,
fabricated, and tested for use with a fiber confocal reflectance microscope. The objective …

Ultra-slim plastic endomicroscope objective for non-linear microscopy

M Kyrish, U Utzinger, MR Descour, BK Baggett… - Optics express, 2011 - opg.optica.org
Non-linear microscopy has the potential to provide clinically useful information on the
structure of biological tissue in vivo via an endomicroscope. The ability to use plastic as the …

Achromatized endomicroscope objective for optical biopsy

M Kyrish, TS Tkaczyk - Biomedical optics express, 2013 - opg.optica.org
Currently, researchers and clinicians lack achromatized endomicroscope objectives that are
as narrow as biopsy needles. We present a proof-of-concept prototype that validates the …