Large-scale production of stem cells utilizing microcarriers: a biomaterials engineering perspective from academic research to commercialized products

H Tavassoli, SN Alhosseini, A Tay, PPY Chan, SKW Oh… - Biomaterials, 2018 - Elsevier
Human stem cells, including pluripotent, embryonic and mesenchymal, stem cells play
pivotal roles in cell-based therapies. Over the past decades, various methods for expansion …

Monolithic DNApatite: An Elastic Apatite with Sub‐Nanometer Scale Organo–Inorganic Structures

JW Lee, B Lee, CH Park, JH Heo, TY Lee… - Advanced …, 2024 - Wiley Online Library
Hydroxyapatite (HA) exhibits outstanding biocompatibility, bioactivity, osteoconductivity, and
natural anti‐inflammatory properties. Pure HA, ion‐doped HA, and HA‐polymer composites …

In situ growth of nano-hydroxyapatite on multilayered Ti3C2Tx MXene as a drug carrier with superior-performance

X Liu, R Sun, Z Zhou, Y Tang - Journal of Materials Science & Technology, 2024 - Elsevier
Bone defects caused by tumor resection typically require bone repair materials to fill the
defect sites. The development of multifunctional bone filling materials with integrated …

Boron-doped biphasic hydroxyapatite/β-tricalcium phosphate for bone tissue engineering

AE Pazarçeviren, A Tezcaner, D Keskin… - … Trace Element Research, 2021 - Springer
Boron-doped hydroxyapatite/tricalcium phosphates (BHTs) were synthesized to study boron
uptake and correlate structural alterations of incremental boron addition (0 to 10 mol%) …

Nanomaterials-based cell osteogenic differentiation and bone regeneration

T Zhang, Y Gao, W Cui, Y Li, D Xiao… - Current Stem Cell …, 2021 - ingentaconnect.com
With the rapid development of nanotechnology, various nanomaterials have been applied to
bone repair and regeneration. Due to the unique chemical, physical and mechanical …

Gelatin/PVP/hydroxyapatite nanocomposite based on double micro-emulsion for tissue engineering applications

SS Nasiri, M Pourmadadi, A Rahdar… - Journal of Molecular …, 2024 - Elsevier
Biomedical applications of composite hydrogels are attractive because of their
characteristics. Gelatin/poly (vinyl pyrrolidone)(PVP) and HAp nanocomposite hydrogel are …

Development and characterization of PLA nanocomposites reinforced with bio-ceramic particles for orthognathic implants: Enhanced mechanical and biological …

R Sharma, N Mehrotra, I Singh, K Pal - International Journal of Biological …, 2024 - Elsevier
The clinical application of osteofixation materials is crucial for maxillofacial reconstruction
and orthognathic surgeries. To overcome the limitations of traditional metallic implants …

Enhanced mechanical properties and hydrophilic behavior of magnesium oxide added hydroxyapatite nanocomposite: A bone substitute material for load bearing …

S Kumar, C Gautam, BS Chauhan, S Srikrishna… - Ceramics …, 2020 - Elsevier
Hydroxyapatite is a multifunctional biomaterial that combines biocompatibility and bioactivity
for various biomedical applications such as bone repairing and bioimaging. In the present …

Potential load-bearing bone substitution material: carbon-fiber-reinforced magnesium-doped hydroxyapatite composites with excellent mechanical performance and …

X Zhao, Z Yang, Q Liu, P Yang, P Wang… - ACS Biomaterials …, 2022 - ACS Publications
A potential load-bearing bone substitution and repair material, that is, carbon fiber (CF)-
reinforced magnesium-doped hydroxyapatite (CF/Mg-HAs) composites with excellent …

Synthesis, structural, mechanical, and biological properties of HAp-ZrO2-hBN biocomposites for bone regeneration applications

A Gautam, C Gautam, M Mishra, S Sahu, R Nanda… - Ceramics …, 2021 - Elsevier
Nowadays researchers are much interested in bioceramics for their use as biological
implants. Researchers have succeeded to derive few bioceramic materials which show …