Equilibrium physics breakdown reveals the active nature of red blood cell flickering

H Turlier, DA Fedosov, B Audoly, T Auth, NS Gov… - Nature physics, 2016 - nature.com
Red blood cells, or erythrocytes, are seen to flicker under optical microscopy, a
phenomenon initially described as thermal fluctuations of the cell membrane. But recent …

Self-assembly of nanoparticles adsorbed on fluid and elastic membranes

A Šarić, A Cacciuto - Soft Matter, 2013 - pubs.rsc.org
In this paper we review recent numerical and theoretical developments of particle self-
assembly on fluid and elastic membranes and compare them to available experimental …

Computational biomechanics of human red blood cells in hematological disorders

X Li, H Li, HY Chang… - Journal of …, 2017 - asmedigitalcollection.asme.org
We review recent advances in multiscale modeling of the biomechanical characteristics of
red blood cells (RBCs) in hematological diseases, and their relevance to the structure and …

Membrane wrapping efficiency of elastic nanoparticles during endocytosis: size and shape matter

Z Shen, H Ye, X Yi, Y Li - ACS nano, 2018 - ACS Publications
Using coarse-grained molecular dynamics simulations, we systematically investigate the
receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging …

Lipid bilayer and cytoskeletal interactions in a red blood cell

Z Peng, X Li, IV Pivkin, M Dao… - Proceedings of the …, 2013 - National Acad Sciences
We study the biomechanical interactions between the lipid bilayer and the cytoskeleton in a
red blood cell (RBC) by developing a general framework for mesoscopic simulations. We …

Erythrocyte membrane model with explicit description of the lipid bilayer and the spectrin network

H Li, G Lykotrafitis - Biophysical journal, 2014 - cell.com
The membrane of the red blood cell (RBC) consists of spectrin tetramers connected at actin
junctional complexes, forming a two-dimensional (2D) sixfold triangular network anchored to …

A dissipative particle dynamics method for arbitrarily complex geometries

Z Li, X Bian, YH Tang, GE Karniadakis - Journal of Computational Physics, 2018 - Elsevier
Dissipative particle dynamics (DPD) is an effective Lagrangian method for modeling
complex fluids in the mesoscale regime but so far it has been limited to relatively simple …

A nonlinear Lagrangian particle model for grains assemblies including grain relative rotations

E Turco, F Dell'Isola, A Misra - International Journal for …, 2019 - Wiley Online Library
We formulate a discrete Lagrangian model for a set of interacting grains, which is purely
elastic. The considered degrees of freedom for each grain include placement of barycenter …

Multiphysics and multiscale modeling of microthrombosis in COVID-19

H Li, Y Deng, Z Li, A Dorken Gallastegi… - PLOS Computational …, 2022 - journals.plos.org
Emerging clinical evidence suggests that thrombosis in the microvasculature of patients with
Coronavirus disease 2019 (COVID-19) plays an essential role in dictating the disease …

In silico and in vitro study of the adhesion dynamics of erythrophagocytosis in sickle cell disease

G Li, Y Qiang, H Li, X Li, M Dao, GE Karniadakis - Biophysical Journal, 2023 - cell.com
Erythrophagocytosis occurring in the spleen is a critical process for removing senescent and
diseased red blood cells (RBCs) from the microcirculation. Although some progress has …