The skin findings seen in lupus erythematosus can present with either lupus-specific or
lupus-nonspecific findings, with lupus-specific skin disease showing findings …

In 1909, the term “lupus erythematodes tumidus” was first introduced by the German
Dermatologist E. Hoffmann. The next case reports of lupus erythematosus tumidus (LET) …

Background There is increased expression of type I interferon (IFN)‐regulated proteins in
the blood and target tissues of patients with cutaneous lupus erythematosus (CLE) and …

54 Annegret Kuhn, Thomas Ruzicka in these designations conform to the classic
dermatologic definitions of these terms. In contrast, LE-nonspecific skin lesions, such as …

Background Lupus erythematosus tumidus (LET) is a rare disease which was first described
in 1909 but has not always been considered as a separate entity of cutaneous lupus …

The 1982 ACR classification criteria have become de facto diagnostic criteria for systemic
lupus erythematosus (SLE), but a review of the criteria is necessary to include recent …

Type I interferons (IFNs) are an immunomodulatory class of cytokines that serve to protect
against viral and bacterial infection. In addition, mounting evidence suggests IFNs …

Lupus erythematosus tumidus (LET) is an uncommon and photosensitive inflammatory skin
disorder which is characterised by erythematous urticarial plaques. In the last 20 years …

Accurate diagnosis of connective tissue diseases is often challenging, and relies upon
careful correlation between clinical and histopathological features, direct …

OBJECTIVE: We sought to identify criteria able to distinguish between Jessner's lymphocytic
infiltration of the skin (JLIS) and lupus erythematosus tumidus (LET). METHODS: The …