Green synthesis, biological and molecular docking of some novel sulfonamide thiadiazole derivatives as potential insecticidal against Spodoptera littoralis

AM El-Saghier, SS Enaili, AM Kadry, A Abdou… - Scientific Reports, 2023 - nature.com
Although crop plants provide the majority of human food, pests and insects frequently cause
huge economic losses. In order to develop innovative insecticidal compounds with low …

Strategies for synthesis of 1, 2, 4-triazole-containing scaffolds using 3-amino-1, 2, 4-triazole

S Nasri, M Bayat, K Kochia - Molecular Diversity, 2022 - Springer
Triazole-containing scaffolds are unique heterocyclic compounds present in an array of
pharmaceuticals and biologically important compounds used in the drug-discovery studies …

Novel 2-acetamido-2-ylidene-4-imidazole derivatives (El-Saghier reaction): Green synthesis, biological assessment, and molecular docking

AM El-Saghier, A Abdou, MAA Mohamed… - ACS …, 2023 - ACS Publications
El-Saghier reaction is the novel, general, and green reaction of various amines with ethyl
cyanoacetate and ethyl glycinate hydrochloride. A new series of imidazolidin-4-ones and bis …

An operationally simple, one‐pot, convenient synthesis, and in vitro anti‐inflammatory activity of some new spirotriazolotriazine derivatives

AM El‐Saghier, SS Enaili, A Abdou… - Journal of …, 2024 - Wiley Online Library
The wide biological actions of triazolotriazine hybrids, benzene‐sulfonamide derivatives,
exhibit a good chance of displaying in vitro anti‐inflammatory effects. An operationally …

An efficient eco-friendly, simple, and green synthesis of some new spiro-N-(4-sulfamoyl-phenyl)-1, 3, 4-thiadiazole-2-carboxamide derivatives as potential inhibitors of …

AM El-Saghier, SS Enaili, A Abdou, AM Kadry - Molecular Diversity, 2024 - Springer
Introduction The coronavirus disease 2019 (COVID-19) pandemic has caused a global
health crisis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a …

Synthesis and antidiabetic activity of novel triazole derivatives containing amino acids

MAA Mohamed, OA Abd Allah… - Journal of …, 2020 - Wiley Online Library
New series of triazole derivatives coupled with amino acids 1a‐h were obtained via
multicomponent reaction of 2‐hydroxy benzaldehyde or 2‐hydroxy acetophenone with …

Synthesis of some new thiadiazole/thiadiazine derivatives as potent biologically active compounds

AM El-Saghier, A Abdul-Baset… - Sohag Journal of …, 2023 - sjsci.journals.ekb.eg
Due to the significant pharmacological and industrial value of 1, 3, 4-thiadiazole and 1, 3, 4-
thiadiazine, they are continuing to be of considerable interest to many researchers, therefore …

Thiadiazole/Thiadiazine Derivatives as Insecticidal Agent: Design, Synthesis, and Biological Assessment of 1, 3, 4-(Thiadiazine/Thiadiazole)-Benzenesulfonamide …

AM El-Saghier, SS Enaili, A Abdou… - Journal of Agricultural …, 2024 - ACS Publications
In keeping with our investigation, a simple and practical synthesis of novel heterocyclic
compounds with a sulfamoyl moiety that can be employed as insecticidal agents was …

Synthesis, docking and biological evaluation of purine-5-N-isosteresas anti-inflammatory agents

AM El-Saghier, SS Enaili, A Abdou, AM Hamed… - RSC …, 2024 - pubs.rsc.org
An operationally simple one-pot three-component and convenient synthesis method for a
series of diverse purine analogues of 5-amino-7-(substituted)-N-(4-sulfamoylphenyl)-4, 7 …

Synthesis, docking and characterization of some novel 5-(S-alkyl)-1.3. 4-thiadiazole-2-carboxamide derivatives as anti-inflammatory and antibacterial agents

AM El-Saghier, A Abdul-Baset, OM El-Hady… - BMC chemistry, 2024 - Springer
Because of the great pharmacological and industrial significance of 1, 3, 4-thiadiazole and
its related compounds, researchers are still very interested in them. For this reason, in this …