Breast cancer (BC) is mostly observed in women and is responsible for huge mortality in
women subjects globally. Due to the continued development of drug resistance and other …

Elevated levels of reactive oxygen species (ROS) are a hallmark of cancer. Although
increased ROS concentrations play important roles in cancer formation and progression …

Human cervical cancer is the fourth most common malignancy among women worldwide,
and it is expected to result in 460,000 deaths per year by 2040. Moreover, patients with …

Metformin increased cellular ROS levels in AsPC-1 pancreatic cancer cells, with minimal
effect in HDF, human primary dermal fibroblasts. Metformin reduced cellular ATP levels in …

Periodontal ligament stem cell (PDLSC)-based tissue engineering is an important method
for regenerating lost bone in periodontitis. Maintaining or enhancing the osteogenic …

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC).
PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are …

Breast cancer is the fifth leading cause of death, worldwide affecting both genders.
Accumulating evidence suggests that metformin, an oral hypoglycemic agent used in the …

Recently, there has been an increase in the incidence of malignant tumors among the older
population. Moreover, there is an association between aging and cancer. During the …

Metformin has been used for a long time as an antidiabetic medication for type 2 diabetes. It
is used either as a monotherapy or in combination with other antidiabetic medications. The …

Breast cancer is one of the most common malignancies in females. It is an etiologically
complex disease driven by a multitude of cellular pathways. The proliferation and spread of …