Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential

N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells that are emerging as the most
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …

Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects

M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Scientific research progress of COVID‐19/SARS‐CoV‐2 in the first five months

H Li, Z Liu, J Ge - Journal of cellular and molecular medicine, 2020 - Wiley Online Library
A cluster of pneumonia (COVID‐19) cases have been found in Wuhan China in late
December, 2019, and subsequently, a novel coronavirus with a positive stranded RNA was …

Immunomodulatory mechanisms and therapeutic potential of mesenchymal stem cells

G Yang, X Fan, Y Liu, P Jie, M Mazhar, Y Liu… - Stem Cell Reviews and …, 2023 - Springer
Mesenchymal stem cells (MSCs) are regarded as highly promising cells for allogeneic cell
therapy, owing to their multipotent nature and ability to display potent and varied functions in …

SARS-CoV-2 infection and lung regeneration

F Zhao, Q Ma, Q Yue, H Chen - Clinical Microbiology Reviews, 2022 - Am Soc Microbiol
The lung is the primary site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2)-induced immunopathology whereby the virus enters the host cells by binding to …

Genetic engineering as a strategy to improve the therapeutic efficacy of mesenchymal stem/stromal cells in regenerative medicine

PKF Damasceno, TSA De Santana… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of
regenerative medicine for applications in the treatment of several disease settings. The …

Immune modulation by transplanted calcium phosphate biomaterials and human mesenchymal stromal cells in bone regeneration

P Humbert, MÁ Brennan, N Davison, P Rosset… - Frontiers in …, 2019 - frontiersin.org
A wide variety of biomaterials have been developed as both stabilizing structures for the
injured bone and inducers of bone neoformation. They differ in chemical composition …

Mesenchymal stem cell immunomodulation: In pursuit of controlling COVID-19 related cytokine storm

N Song, H Wakimoto, F Rossignoli, D Bhere… - Stem Cells, 2021 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has grown to be a global
public health crisis with no safe and effective treatments available yet. Recent findings …

Intratracheal administration of clinical-grade mesenchymal stem cell-derived extracellular vesicles reduces lung injury in a rat model of bronchopulmonary dysplasia

A Porzionato, P Zaramella, A Dedja… - … of Physiology-Lung …, 2019 - journals.physiology.org
Mesenchymal stem cells (MSCs) prevent the onset of bronchopulmonary dysplasia (BPD) in
animal models, an effect that seems to be mediated by their secreted extracellular vesicles …