Highlights•Persistent Puumala virus shedding occurs in wild voles.•Host population density
thresholds estimated for hantavirus invasion.•Little is known about hantavirus transmission …

Finland has the highest incidence of hantavirus infections globally, with a significant impact
on public health. The large coverage of boreal forests and the cyclic dynamics of the …

Gut microbiota play an important role in host health. Yet, the drivers and patterns of
microbiota imbalance (dysbiosis) in wild animals remain largely unexplored. One …

Identifying factors that drive infection dynamics in reservoir host populations is essential in
understanding human risk from wildlife-originated zoonoses. We studied zoonotic Puumala …

Understanding the dynamics of zoonotic pathogens in their reservoir host populations is a
prerequisite for predicting and preventing human disease epidemics. The human infection …

Orthohantaviruses give rise to the emerging infections such as of hemorrhagic fever with
renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) in Eurasia and the …

The Costa Rican pygmy rice rat (Oligoryzomys costaricensis) is the primary reservoir of
Choclo orthohantavirus (CHOV), the causal agent of hantavirus disease, pulmonary …

The effects of systemic pathogens on gut microbiota of wild animals are poorly understood.
Furthermore, coinfections are the norm in nature, yet most studies of pathogen–microbiota …

Most human pathogenic hantaviruses cause severe hemorrhagic fevers with a high rate of
fatalities, such as occurs due to the genotypes causing hantavirus cardiopulmonary …

Background Rodent-borne hantaviruses (genus Orthohantavirus) are the etiologic agents
causing two human diseases: hemorrhagic fever with renal syndrome (HFRS) in Euroasia; …