Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …

Transcriptome sequencing or RNA-Sequencing is a high-resolution, sensitive and high-
throughput next-generation sequencing (NGS) approach used to study non-model plants …

Assembling high-quality microbial genomes using only cost-effective Nanopore long-read
systems such as Flongle is important to accelerate research on the microbial genome and …

Background The long reads of the third-generation sequencing significantly benefit the
quality of the de novo genome assembly. However, its relatively high single-base error rate …

In recent years, the delicate balance between economic development and ecological
environment protection in ecologically fragile arid areas has gradually become apparent …

Abstract RNA 5-hydroxymethylcytosine (5hmC) is a kind of RNA modification, which is
related to the life activities of many organisms. Studying its distribution is very important to …

Abstract Motivation 5-Methylcytosine (m5C) is a crucial post-transcriptional modification.
With the development of technology, it is widely found in various RNAs. Numerous studies …

The side effects of drugs present growing concern attention in the healthcare system.
Accurately identifying the side effects of drugs is very important for drug development and …

Metagenome assembly is an efficient approach to reconstruct microbial genomes from
metagenomic sequencing data. Although short-read sequencing has been widely used for …

Next-generation DNA and RNA sequencing has revolutionized biology and medicine. With
sequencing costs continuously dropping and our ability to generate large datasets rising …