Complicated Surgical Site Infection with Mycobacterium Abscessus After Liposuction and Affections of Corticosteroids in the Treatment Regimen: Three Cases Report …

HT Tuan, NA Ngoc, LD Ai, N Van Luat - Aesthetic Plastic Surgery, 2024 - Springer
Introduction Mycobacterium abscessus infection after liposuction/fat grafting is a rare
complication that is hard to diagnose and treat. Misdiagnosis could result in treatment failure …

Review of the Effectiveness of Various Adjuvant Therapies in Treating Mycobacterium tuberculosis

A Amin, A Vartanian, A Yegiazaryan… - Infectious disease …, 2021 - mdpi.com
Tuberculosis disease is caused by the bacterium Mycobacterium tuberculosis. It is estimated
that 10 million people have developed tuberculosis disease globally, leading to 1.4 million …

Low-cost anti-mycobacterial drug discovery using engineered E. coli

N Bongaerts, Z Edoo, AA Abukar, X Song… - Nature …, 2022 - nature.com
Whole-cell screening for Mycobacterium tuberculosis (Mtb) inhibitors is complicated by the
pathogen's slow growth and biocontainment requirements. Here we present a synthetic …

α1-Antitrypsin binds to the glucocorticoid receptor with anti-inflammatory and antimycobacterial significance in macrophages

X Bai, A Bai, M Tomasicchio, JR Hagman… - The Journal of …, 2022 - journals.aai.org
Abstract α1-Antitrypsin (AAT), a serine protease inhibitor, is the third most abundant protein
in plasma. Although the best-known function of AAT is irreversible inhibition of elastase, AAT …

PDCD4 as a marker of mTOR pathway activation and therapeutic target in mycobacterial infections

R Paroha, J Wang, S Lee - Microbiology Spectrum, 2024 - journals.asm.org
Programmed cell death protein 4 (PDCD4) is instrumental in regulating a range of cellular
processes such as translation, apoptosis, signal transduction, and inflammatory responses …

Glucocorticoid alleviates hypothalamic nerve injury via remodeling HPA axis homeostasis in stressed rats

S Yi, B Zhao, L Wei, Z Yao, B Yang - Behavioural Brain Research, 2024 - Elsevier
Excessive stress can exceed the adjustment ability of body and cause injury and
dysfunction, while elucidation of the mechanism and prevention measures of stress-related …

[HTML][HTML] Metabolites enhance innate resistance to human Mycobacterium tuberculosis infection

D Tripathi, KP Devalraju, VSK Neela, T Mukherjee… - JCI insight, 2022 - ncbi.nlm.nih.gov
To determine the mechanisms that mediate resistance to Mycobacterium tuberculosis (M.
tuberculosis) infection in household contacts (HHCs) of patients with tuberculosis (TB), we …

Morphology of Lymphoid Tissue in the Lungs of Guinea Pigs Infected with Mycobacterium bovis against the Background of Vaccine Immunity and the Action of Betulin …

IN Koshkin, VS Vlasenko, VI Pleshakova, LE Alkhimova… - Vaccines, 2022 - mdpi.com
Tuberculosis caused by Mycobacterium bovis is a serious problem for animal and human
health worldwide. A promising concept for the design of anti-tuberculosis drugs is the …

Effect of Low Doses of Dexamethasone on Experimental Pulmonary Tuberculosis

JV Lara-Espinosa, MF Arce-Aceves, J Barrios-Payán… - Microorganisms, 2023 - mdpi.com
Tuberculosis (TB) is the deadliest disease caused by a bacterial agent. Glucocorticoids
(GCs) have a typical anti-inflammatory effect, but recently it has been shown that they can …

Alpha-1-antitrypsin binds to the glucocorticoid receptor with biological significance in macrophages

X Bai, A Bai, M Tomasicchio, JR Hagman, AM Buckle… - bioRxiv, 2022 - biorxiv.org
ABSTRACT Alpha-1-antitrypsin (AAT), a serine protease inhibitor produced mainly by the
liver, is the third most abundant protein in plasma. While a canonical receptor for AAT has …