Protozoan parasite diseases cause significant mortality and morbidity worldwide. Factors
such as climate change, extreme poverty, migration, and a lack of life opportunities lead to …

Giardia duodenalis is a flagellated unicellular eukaryotic microorganism that usually
parasitizes the small intestine of humans and many other vertebrates causing diarrheal …

Abstract Background Metronidazole (Mtz) is the frontline drug treatment for multiple
anaerobic pathogens, including the gastrointestinal protist, Giardia duodenalis. However …

This review considers current advances in tools to investigate the functional biology of
Giardia, it's coding and non-coding genes, features and cellular and molecular biology. We …

Diarrheal disease caused by Giardia duodenalis is highly prevalent, causing over 200
million cases globally each year. The processes that drive parasite virulence, host immune …

In eukaryotes, genomic DNA is bound with histone proteins and packaged into chromatin.
The nucleosome, a fundamental unit of chromatin, regulates the accessibility of DNA to …

Methylation is a common posttranslational modification of arginine and lysine in eukaryotic
proteins. Methylproteomes are best characterized for higher eukaryotes, where they are …

Giardia duodenalis is a parasite of great medical interest due to the number of infections it
causes worldwide each year. Although research on epigenetic mechanisms in this protist …

Background SET domain-containing histone lysine methyltransferases (HKMTs) and JmjC
domain-containing histone demethylases (JHDMs) are essential for maintaining dynamic …

Histone post-translational modifications are extensively studied for their role in regulating
gene transcription and cellular environmental adaptation. Research into these modifications …