Abstract THROUGH THE STUDY of uncommon familial syndromes, physicians and
scientists have been able to illuminate the underlying mechanisms of some of the more …

Retinoblastoma (Rb), the most common intraocular tumor of childhood, is a highly malignant
retinal tumor. 33 The manner of intraocular and extraocular extension, the patterns of …

PURPOSE: To obtain refined knowledge regarding trilateral retinoblastoma (TRb), which is
a syndrome that consists of hereditary retinoblastoma associated with an intracranial …

Objective To evaluate whether neoadjuvant intravenous chemotherapy (chemoreduction) for
retinoblastoma reduces the risk for associated intracranial neuroblastic tumor (trilateral …

BACKGROUND Trilateral retinoblastoma refers to bilateral retinoblastoma associated with
an intracranial primitive neuroectodermal tumor in the pineal or suprasellar region. The …

Retinoblastoma (Rb) is a malignant tumor of childhood that was first described in the
sixteenth century [1]. Now, it is the most common intraocular tumor in children [2, 3] and …

Purpose: To evaluate the role of pre-and post-contrast magnetic resonance (MR) studies in
children with intraocular tumors and simulating lesions. Methods: Patients younger than 12 …

Trilateral retinoblastoma (TRb) is a rare disease associating intraocular retinoblastoma with
intracranial primitive neuroectodermal tumor. Treatment is difficult and prognosis is poor …

OBJECTIVE. The purpose of this study was to assess the clinical and radiologic features of
tumor progression in children with trilateral retinoblastoma. MATERIALS AND METHODS …

We conducted a systematic review of 72 studies to characterize trilateral retinoblastomas.
Kaplan-Meier analysis was used to estimate survival, and statistical significance was …