Current strategies in assessment of nanotoxicity: alternatives to in vivo animal testing

HJ Huang, YH Lee, YH Hsu, CT Liao, YF Lin… - International journal of …, 2021 - mdpi.com
Millions of experimental animals are widely used in the assessment of toxicological or
biological effects of manufactured nanomaterials in medical technology. However, the …

Ethical, legal, regulatory, and policy issues concerning embryoids: a systematic review of the literature

AS Iltis, G Koster, E Reeves, KRW Matthews - Stem Cell Research & …, 2023 - Springer
Recent advances in methods to culture pluripotent stem cells to model human development
have resulted in entities that increasingly have recapitulated advanced stages of early …

Human placenta-derived mesenchymal stem cells transplantation in patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 (phase I clinical …

HR Aghayan, F Salimian, A Abedini… - Stem cell research & …, 2022 - Springer
Background High morbidity and mortality rates of the COVID-19 pandemic have made it a
global health priority. Acute respiratory distress syndrome (ARDS) is one of the most …

The ethical implications of tissue engineering for regenerative purposes: A systematic review

AFJ de Kanter, KR Jongsma, MC Verhaar… - … Engineering Part B …, 2023 - liebertpub.com
Tissue Engineering (TE) is a branch of Regenerative Medicine (RM) that combines stem
cells and biomaterial scaffolds to create living tissue constructs to restore patients' organs …

Alternatives of animal models for biomedical research: a comprehensive review of modern approaches

A Vashishat, P Patel, G Das Gupta… - Stem Cell Reviews and …, 2024 - Springer
Biomedical research has long relied on animal models to unravel the intricacies of human
physiology and pathology. However, concerns surrounding ethics, expenses, and inherent …

New solutions for old problems: how reproductive tissue engineering has been revolutionizing reproductive medicine

ECR Leonel, A Dadashzadeh, S Moghassemi… - Annals of biomedical …, 2023 - Springer
Acquired disorders and congenital defects of the male and female reproductive systems can
have profound impacts on patients, causing sexual and endocrine dysfunction and infertility …

Comparisons between plant and animal stem cells regarding regeneration potential and application

L Liu, L Qiu, Y Zhu, L Luo, X Han, M Man, F Li… - International Journal of …, 2023 - mdpi.com
Regeneration refers to the process by which organisms repair and replace lost tissues and
organs. Regeneration is widespread in plants and animals; however, the regeneration …

[HTML][HTML] Early-phase clinical trials of bio-artificial organ technology: a systematic review of ethical issues

D de Jongh, EK Massey, AJ Cronin… - Transplant …, 2022 - frontierspartnerships.org
Regenerative medicine has emerged as a novel alternative solution to organ failure which
circumvents the issue of organ shortage. In preclinical research settings bio-artificial organs …

Inclusivity and diversity: Integrating international perspectives on stem cell challenges and potential

R Fears, H Akutsu, LT Alentajan-Aleta, A Caicedo… - Stem Cell Reports, 2021 - cell.com
Regenerative medicine has great potential. The pace of scientific advance is exciting and
the medical opportunities for regeneration and repair may be transformative. However …

PRP, Exosomes, and Stem Cells: An International Perspective

N Singh, AN Brown, MH Gold - Dermatological Reviews, 2024 - Wiley Online Library
Background Regenerative medicine is a novel, developing field centered on efforts to
repurpose the body's own molecular makeup to target specific problems. Specifically, the …